Flora Meilleur

Expression, purification, assay, and crystal structure of perdeuterated human arginase I.

Deuterium labeling for neutron structure-function-dynamics analysis.

The structure of Sindbis virus produced from vertebrate and invertebrate hosts as determined by small-angle neutron scattering.

Crystallization and preliminary X-ray diffraction analysis of red clover necrotic mosaic virus.

Conformational changes in Sindbis virus induced by decreased pH are revealed by small-angle neutron scattering.

Open conformation of ezrin bound to phosphatidylinositol 4,5-bisphosphate and to F-actin revealed by neutron scattering.

New insight into the structure of RNA in red clover necrotic mosaic virus and the role of divalent cations revealed by small-angle neutron scattering.

Refinement of macromolecular structures against neutron data with

Crystallization and preliminary X-ray diffraction analysis of Hypocrea jecorina Cel7A in two new crystal forms.

Production and characterization of recombinant perdeuterated cholesterol oxidase.

Neutron Crystal Structure of RAS GTPase Puts in Question the Protonation State of the GTP γ-Phosphate.

Neutron protein crystallography: A complementary tool for locating hydrogens in proteins.

Crystal structures of wild-type Trichoderma reesei Cel7A catalytic domain in open and closed states.

Oxygen Activation at the Active Site of a Fungal Lytic Polysaccharide Monooxygenase.

An extended N-H bond, driven by a conserved second-order interaction, orients the flavin N5 orbital in cholesterol oxidase.

Crystallization of a fungal lytic polysaccharide monooxygenase expressed from glycoengineered Pichia pastoris for X-ray and neutron diffraction.

Structural studies of Neurospora crassa LPMO9D and redox partner CDHIIA using neutron crystallography and small-angle scattering.

Neutron structure of the T26H mutant of T4 phage lysozyme provides insight into the catalytic activity of the mutant enzyme and how it differs from that of wild type.

Neutron crystallographic studies of T4 lysozyme at cryogenic temperature.

Structural investigation of cellobiose dehydrogenase IIA: Insights from small angle scattering into intra- and intermolecular electron transfer mechanisms.

Modulating Enzyme Activity by Altering Protein Dynamics with Solvent.

IMAGINE: neutrons reveal enzyme chemistry.

Titration of ionizable groups in proteins using multiple neutron data sets from a single crystal: application to the small GTPase Ras.

Neutron and X-ray analysis of the Fenna-Matthews-Olson photosynthetic antenna complex from Prosthecochloris aestuarii.

Dynamic nuclear polarization enhanced neutron crystallography: Amplifying hydrogen in biological crystals.

IMAGINE: The neutron protein crystallography beamline at the high flux isotope reactor.

Preliminary results of neutron and X-ray diffraction data collection on a lytic polysaccharide monooxygenase under reduced and acidic conditions.

Metalloprotein catalysis: structural and mechanistic insights into oxidoreductases from neutron protein crystallography.

The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and X-ray diffraction at room temperature.

The P132H mutation in the main protease of Omicron SARS-CoV-2 decreases thermal stability without compromising catalysis or small-molecule drug inhibition.

The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature.

Changes in active-site geometry on X-ray photoreduction of a lytic polysaccharide monooxygenase active-site copper and saccharide binding.

Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature.

Mapping H in the Nanoscale (AC)-Ag Fluorophore.

Capture of activated dioxygen intermediates at the copper-active site of a lytic polysaccharide monooxygenase.

Joint X-ray/neutron structure of Lentinus similis AA9_A at room temperature.