Birte Kalveram

FAT10, a ubiquitin-independent signal for proteasomal degradation.

The UBA domains of NUB1L are required for binding but not for accelerated degradation of the ubiquitin-like modifier FAT10.

The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition.

Degradation of FAT10 by the 26S proteasome is independent of ubiquitylation but relies on NUB1L.

USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis.

NSs protein of rift valley fever virus promotes posttranslational downregulation of the TFIIH subunit p62.

The dominant-negative inhibition of double-stranded RNA-dependent protein kinase PKR increases the efficacy of Rift Valley fever virus MP-12 vaccine.

The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation.

Functional analysis of Rift Valley fever virus NSs encoding a partial truncation.

Rift Valley fever virus NSs inhibits host transcription independently of the degradation of dsRNA-dependent protein kinase PKR.

Toscana virus NSs protein promotes degradation of double-stranded RNA-dependent protein kinase.

Rift Valley fever virus MP-12 vaccine encoding Toscana virus NSs retains neuroinvasiveness in mice.

Characterization of Rift Valley fever virus MP-12 strain encoding NSs of Punta Toro virus or sandfly fever Sicilian virus.