Khalid Salaita

Roles of the cytoskeleton in regulating EphA2 signals.

Nanomedicine in GI.

Using patterned supported lipid membranes to investigate the role of receptor organization in intercellular signaling.

L-Ala-γ-D-Glu-meso-diaminopimelic acid (DAP) interacts directly with leucine-rich region domain of nucleotide-binding oligomerization domain 1, increasing phosphorylation activity of receptor-interacting serine/threonine-protein kinase 2 and its interaction with nucleotide-binding oligomerization domain 1.

Visualizing mechanical tension across membrane receptors with a fluorescent sensor.

Catalytic deoxyribozyme-modified nanoparticles for RNAi-independent gene regulation.

Tension sensing nanoparticles for mechano-imaging at the living/nonliving interface.

Membrane tethered delta activates notch and reveals a role for spatio-mechanical regulation of the signaling pathway.

Quantum dots encapsulated within phospholipid membranes: phase-dependent structure, photostability, and site-selective functionalization.

Structurally defined nanoscale sheets from self-assembly of collagen-mimetic peptides.

Integrin-generated forces lead to streptavidin-biotin unbinding in cellular adhesions.

The modulation of cardiac progenitor cell function by hydrogel-dependent Notch1 activation.

Nanoparticle tension probes patterned at the nanoscale: impact of integrin clustering on force transmission.

DNA-based digital tension probes reveal integrin forces during early cell adhesion.

Lighting Up the Force: Investigating Mechanisms of Mechanotransduction Using Fluorescent Tension Probes.

Real-time fluorescence imaging with 20 nm axial resolution.

Titin-Based Nanoparticle Tension Sensors Map High-Magnitude Integrin Forces within Focal Adhesions.

High-speed DNA-based rolling motors powered by RNase H.

Nanoscale optomechanical actuators for controlling mechanotransduction in living cells.

Knockdown of TNF-α by DNAzyme gold nanoparticles as an anti-inflammatory therapy for myocardial infarction.

A General Approach for Generating Fluorescent Probes to Visualize Piconewton Forces at the Cell Surface.

Mechanically Induced Catalytic Amplification Reaction for Readout of Receptor-Mediated Cellular Forces.

DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity.

Ratiometric Tension Probes for Mapping Receptor Forces and Clustering at Intermembrane Junctions.

Supported lipid bilayer platforms to probe cell mechanobiology.

Site-Selective RNA Splicing Nanozyme: DNAzyme and RtcB Conjugates on a Gold Nanoparticle.

Molecular Tension Probes for Imaging Forces at the Cell Surface.

Mapping the 3D orientation of piconewton integrin traction forces.

Platelet integrins exhibit anisotropic mechanosensing and harness piconewton forces to mediate platelet aggregation.

Light-Responsive Polymer Particles as Force Clamps for the Mechanical Unfolding of Target Molecules.

Molecular Tension Probes to Investigate the Mechanopharmacology of Single Cells: A Step toward Personalized Mechanomedicine.

Programmable Multivalent DNA-Origami Tension Probes for Reporting Cellular Traction Forces.

A brighter force gauge for cells.

Location, Location, Location: EphB4:Ephrin-B2 Signaling Depends on Its Spatial Arrangement.

A TCR mechanotransduction signaling loop induces negative selection in the thymus.

Localized Nanoscale Heating Leads to Ultrafast Hydrogel Volume-Phase Transition.

DNA Nanotechnology as an Emerging Tool to Study Mechanotransduction in Living Systems.

2D Crystal Engineering of Nanosheets Assembled from Helical Peptide Building Blocks.

Mechanical Proofreading: A General Mechanism to Enhance the Fidelity of Information Transfer Between Cells.

Macrophages exposed to HIV viral protein disrupt lung epithelial cell integrity and mitochondrial bioenergetics via exosomal microRNA shuttling.

DNA probes that store mechanical information reveal transient piconewton forces applied by T cells.

Highly Polyvalent DNA Motors Generate 100+ pN of Force via Autochemophoresis.

Chameleon-Inspired Strain-Accommodating Smart Skin.

Emerging uses of DNA mechanical devices.

DNA mechanotechnology reveals that integrin receptors apply pN forces in podosomes on fluid substrates.

Seeded Heteroepitaxial Growth of Crystallizable Collagen Triple Helices: Engineering Multifunctional Two-Dimensional Core-Shell Nanostructures.

Forces during cellular uptake of viruses and nanoparticles at the ventral side.

Tunable DNA Origami Motors Translocate Ballistically Over μm Distances at nm/s Speeds.

Engineering DNA-Functionalized Nanostructures to Bind Nucleic Acid Targets Heteromultivalently with Enhanced Avidity.

Optical Control of Cytokine Signaling via Bioinspired, Polymer-Induced Latency.

Super-Resolution Fluorescence Imaging Reveals That Serine Incorporator Protein 5 Inhibits Human Immunodeficiency Virus Fusion by Disrupting Envelope Glycoprotein Clusters.

EGFR activation attenuates the mechanical threshold for integrin tension and focal adhesion formation.

Mechanical Stimulation of Adhesion Receptors Using Light-Responsive Nanoparticle Actuators Enhances Myogenesis.

Conditional Deoxyribozyme-Nanoparticle Conjugates for miRNA-Triggered Gene Regulation.

Live-cell super-resolved PAINT imaging of piconewton cellular traction forces.

Shape-Shifting Peptide Nanomaterials: Surface Asymmetry Enables pH-Dependent Formation and Interconversion of Collagen Tubes and Sheets.

Multivalent molecular tension probes as anisotropic mechanosensors: concept and simulation.

Spectroscopic Analysis of a Library of DNA Tension Probes for Mapping Cellular Forces at Fluid Interfaces.