Muniswamy Madesh

Rapid kinetics of tBid-induced cytochrome c and Smac/DIABLO release and mitochondrial depolarization.

TGF-beta-induced Ca(2+) influx involves the type III IP(3) receptor and regulates actin cytoskeleton.

tcBid promotes Ca(2+) signal propagation to the mitochondria: control of Ca(2+) permeation through the outer mitochondrial membrane.

Calcium signaling and apoptosis.

The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein.

Involvement of transforming growth factor-beta in regulation of calcium transients in diabetic vascular smooth muscle cells.

A surfactant protein C precursor protein BRICHOS domain mutation causes endoplasmic reticulum stress, proteasome dysfunction, and caspase 3 activation.

Proliferative signaling by store-operated calcium channels opposes colon cancer cell cytostasis induced by bacterial enterotoxins.

Lung endothelial cell proliferation with decreased shear stress is mediated by reactive oxygen species.

The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R.

Selective role for superoxide in InsP3 receptor-mediated mitochondrial dysfunction and endothelial apoptosis.

Functional and trafficking defects in ATP binding cassette A3 mutants associated with respiratory distress syndrome.

The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1.

Superoxide flux in endothelial cells via the chloride channel-3 mediates intracellular signaling.

ABCA3 is critical for lamellar body biogenesis in vivo.

The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis.

G protein-coupled receptor Ca2+-linked mitochondrial reactive oxygen species are essential for endothelial/leukocyte adherence.

Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy.

Endothelial targeting of semi-permeable polymer nanocarriers for enzyme therapies.

The common inhalational anesthetic isoflurane induces apoptosis via activation of inositol 1,4,5-trisphosphate receptors.

Caveolae are an essential component of the pathway for endothelial cell signaling associated with abrupt reduction of shear stress.

Inhalational anesthetics induce cell damage by disruption of intracellular calcium homeostasis with different potencies.

Bad targets the permeability transition pore independent of Bax or Bak to switch between Ca2+-dependent cell survival and death.

Carcinoembryonic cell adhesion molecule 6 in human lung: regulated expression of a multifunctional type II cell protein.

Execution of superoxide-induced cell death by the proapoptotic Bcl-2-related proteins Bid and Bak.

Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers.

Nitration of the mitochondrial complex I subunit NDUFB8 elicits RIP1- and RIP3-mediated necrosis.

Mitochondrial complex II prevents hypoxic but not calcium- and proapoptotic Bcl-2 protein-induced mitochondrial membrane potential loss.

S-glutathionylation activates STIM1 and alters mitochondrial homeostasis.

PECAM-targeted delivery of SOD inhibits endothelial inflammatory response.

Acidic NAADP-sensitive calcium stores in the endothelium: agonist-specific recruitment and role in regulating blood pressure.

NF-kappaB protects cells from gamma interferon-induced RIP1-dependent necroptosis.

Hyperhomocysteinemia impairs endothelium-derived hyperpolarizing factor-mediated vasorelaxation in transgenic cystathionine beta synthase-deficient mice.

Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis.

Sensing cellular stress through STIM proteins.

Hypoxia-induced acidosis uncouples the STIM-Orai calcium signaling complex.

Membrane-Tethered MUC1 Mucin Is Phosphorylated by Epidermal Growth Factor Receptor in Airway Epithelial Cells and Associates with TLR5 To Inhibit Recruitment of MyD88.