Orlando Laitano

Hyperthermia, dehydration, and osmotic stress: unconventional sources of exercise-induced reactive oxygen species.

Pharmacological targeting of mitochondrial reactive oxygen species counteracts diaphragm weakness in chronic heart failure.

The Impact of Hyperthermia on Receptor-Mediated Interleukin-6 Regulation in Mouse Skeletal Muscle.

Regulation of NADPH oxidases in skeletal muscle.

Xiphoid Surface Temperature Predicts Mortality in a Murine Model of Septic Shock.

Epinephrine stimulates CXCL1 IL-1, IL-6 secretion in isolated mouse limb muscle.

Sex-dependent responses to exertional heat stroke in mice.

Osmolality Selectively Offsets the Impact of Hyperthermia on Mouse Skeletal Muscle .

Controversies in exertional heat stroke diagnosis, prevention, and treatment.

Delayed metabolic dysfunction in myocardium following exertional heat stroke in mice.

Effects of Ibuprofen during Exertional Heat Stroke in Mice.

Acute phase response to exertional heat stroke in mice.

Overlapping Mechanisms of Exertional Heat Stroke and Malignant Hyperthermia: Evidence vs. Conjecture.

Septic Stability? Gut Microbiota in Young Adult Mice Maintains Overall Stability After Sepsis Compared to Old Adult Mice.

Exertional heat stroke leads to concurrent long-term epigenetic memory, immunosuppression and altered heat shock response in female mice.

Skeletal muscle fibers play a functional role in host defense during sepsis in mice.

Pathophysiology and Treatment Strategies of Acute Myopathy and Muscle Wasting after Sepsis.

Skeletal Muscle Interleukin-6 Contributes to the Innate Immune Response in Septic Mice.

The impact of hindlimb disuse on sepsis-induced myopathy in mice.

Sepsis-Induced Myopathy and Gut Microbiome Dysbiosis: Mechanistic Links and Therapeutic Targets.

Lipopolysaccharide-Induced Cytokine Secretion from In Vitro Mouse Slow and Fast Limb Muscle.

Sex differences associate with late microbiome alterations after murine surgical sepsis.

Human temperature regulation under heat stress in health, disease, and injury.

The effect of interval and continuous work on markers of acute kidney injury in a hot environment.

The effect of prolonged interval and continuous exercise in the heat on circulatory markers of intestinal barrier integrity.

Heat stroke: physiological challenges and breakthroughs.

The impact of castration on physiological responses to exertional heat stroke in mice.

Neuromotor deficits and altered physiological responses to repeated exertional heat stroke exposures in mice.

Blocking muscle wasting via deletion of the muscle-specific E3 ubiquitin ligase MuRF1 impedes pancreatic tumor growth.

Exertional heat stroke: pathophysiology and risk factors.

Ovariectomy aggravates the pathophysiological response to exertional heat stroke in mice.

Blocking muscle wasting via deletion of the muscle-specific E3 ligase MuRF1 impedes pancreatic tumor growth.

Activation of the Aryl Hydrocarbon Receptor in Endothelial Cells Impairs Ischemic Angiogenesis in Chronic Kidney Disease.

Deletion of the aryl hydrocarbon receptor in endothelial cells improves ischemic angiogenesis in chronic kidney disease.

Exertional heat stroke causes long-term skeletal muscle epigenetic reprogramming, altered gene expression, and impaired satellite cell function in mice.

Consideration of sex as a biological variable in the context of thermal physiology and biometeorological research.

There's a seat at the table for all! Converging disciplines toward understanding and mitigating heat-related mortality.