Gregory Dussor

Evolution: the advantage of 'maladaptive' pain plasticity.

Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity.

Targeting TRP channels for novel migraine therapeutics.

ASICs as therapeutic targets for migraine.

Meningeal norepinephrine produces headache behaviors in rats via actions both on dural afferents and fibroblasts.

Protease-activated receptor 2 activation is sufficient to induce the transition to a chronic pain state.

Meningeal afferent signaling and the pathophysiology of migraine.

Spinal dopaminergic projections control the transition to pathological pain plasticity via a D1/D5-mediated mechanism.

Meningeal transient receptor potential channel M8 activation causes cutaneous facial and hindpaw allodynia in a preclinical rodent model of headache.

Adenosine Monophosphate-activated Protein Kinase (AMPK) Activators For the Prevention, Treatment and Potential Reversal of Pathological Pain.

Neurovascular contributions to migraine: Moving beyond vasodilation.

TRPM8 and Migraine.

The potent, indirect adenosine monophosphate- activated protein kinase activator R419 attenuates mitogen-activated protein kinase signaling, inhibits nociceptor excitability, and reduces pain hypersensitivity in mice.

Targeting AMPK for the Alleviation of Pathological Pain.

Dural stimulation in rats causes brain-derived neurotrophic factor-dependent priming to subthreshold stimuli including a migraine trigger.

Stretchable multichannel antennas in soft wireless optoelectronic implants for optogenetics.

The AMPK Activator A769662 Blocks Voltage-Gated Sodium Channels: Discovery of a Novel Pharmacophore with Potential Utility for Analgesic Development.

The MNK-eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain.

Pharmacological activation of AMPK inhibits incision-evoked mechanical hypersensitivity and the development of hyperalgesic priming in mice.

A Critical Role for Dopamine D5 Receptors in Pain Chronicity in Male Mice.

17-β-Estradiol induces spreading depression and pain behavior in alert female rats.

eIF4E Phosphorylation Influences mRNA Translation in Mouse Dorsal Root Ganglion Neurons.

Targeted Acid-Sensing Ion Channel Therapies for Migraine.

Comparative transcriptome profiling of the human and mouse dorsal root ganglia: an RNA-seq-based resource for pain and sensory neuroscience research.

Protease activated receptor 2 (PAR2) activation causes migraine-like pain behaviors in mice.

Spinal Inhibition of P2XR or p38 Signaling Disrupts Hyperalgesic Priming in Male, but not Female, Mice.

Adult mouse sensory neurons on microelectrode arrays exhibit increased spontaneous and stimulus-evoked activity in the presence of interleukin-6.

Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain.

Activation of the integrated stress response in nociceptors drives methylglyoxal-induced pain.

Pituitary Hormones and Orofacial Pain.

The antidiabetic drug metformin prevents and reverses neuropathic pain and spinal cord microglial activation in male but not female mice.

Nociceptor Translational Profiling Reveals the Ragulator-Rag GTPase Complex as a Critical Generator of Neuropathic Pain.

Emerging neurotechnology for antinoceptive mechanisms and therapeutics discovery.

Electrophysiological and transcriptomic correlates of neuropathic pain in human dorsal root ganglion neurons.

Transcriptome Analysis of the Human Tibial Nerve Identifies Sexually Dimorphic Expression of Genes Involved in Pain, Inflammation, and Neuro-Immunity.

Dural Calcitonin Gene-Related Peptide Produces Female-Specific Responses in Rodent Migraine Models.

TRP Channels and Migraine: Recent Developments and New Therapeutic Opportunities.

AMPK activation regulates P-body dynamics in mouse sensory neurons and .

Temporal and sex differences in the role of BDNF/TrkB signaling in hyperalgesic priming in mice and rats.

Sex differences in the expression of calcitonin gene-related peptide receptor components in the spinal trigeminal nucleus.

Prolactin receptor expression in mouse dorsal root ganglia neuronal subtypes is sex-dependent.

Differences between Dorsal Root and Trigeminal Ganglion Nociceptors in Mice Revealed by Translational Profiling.

Indirect AMP-Activated Protein Kinase Activators Prevent Incision-Induced Hyperalgesia and Block Hyperalgesic Priming, Whereas Positive Allosteric Modulators Block Only Priming in Mice.

MNK-eIF4E signalling is a highly conserved mechanism for sensory neuron axonal plasticity: evidence from .

Reversal of peripheral nerve injury-induced neuropathic pain and cognitive dysfunction via genetic and tomivosertib targeting of MNK.

Prolactin Regulates Pain Responses via a Female-Selective Nociceptor-Specific Mechanism.

Alleviation of paclitaxel-induced mechanical hypersensitivity and hyperalgesic priming with AMPK activators in male and female mice.

Mycobacterium tuberculosis Sulfolipid-1 Activates Nociceptive Neurons and Induces Cough.

Pharmacological target-focused transcriptomic analysis of native vs cultured human and mouse dorsal root ganglia.

Type I Interferons Act Directly on Nociceptors to Produce Pain Sensitization: Implications for Viral Infection-Induced Pain.

The cellular basis of protease-activated receptor 2-evoked mechanical and affective pain.

A pharmacological interactome between COVID-19 patient samples and human sensory neurons reveals potential drivers of neurogenic pulmonary dysfunction.

IL-6 induced upregulation of T-type Ca currents and sensitization of DRG nociceptors is attenuated by MNK inhibition.

Repetitive stress in mice causes migraine-like behaviors and calcitonin gene-related peptide-dependent hyperalgesic priming to a migraine trigger.

Neuroendocrine Mechanisms Governing Sex Differences in Hyperalgesic Priming Involve Prolactin Receptor Sensory Neuron Signaling.

Transcriptomic sex differences in sensory neuronal populations of mice.

protein synthesis is necessary for priming in preclinical models of migraine.

Sex Differences in Nociceptor Translatomes Contribute to Divergent Prostaglandin Signaling in Male and Female Mice.

A Role for Protease Activated Receptor Type 3 (PAR3) in Nociception Demonstrated Through Development of a Novel Peptide Agonist.

A ligand-receptor interactome platform for discovery of pain mechanisms and therapeutic targets.

Meningeal CGRP-Prolactin Interaction Evokes Female-Specific Migraine Behavior.

Diversity of Receptor Expression in Central and Peripheral Mouse Neurons Estimated from Single Cell RNA Sequencing.

Transient receptor potential canonical 5 mediates inflammatory mechanical and spontaneous pain in mice.

Voluntary Wheel Running Partially Attenuates Early Life Stress-Induced Neuroimmune Measures in the Dura and Evoked Migraine-Like Behaviors in Female Mice.

Interleukin-6 induces spatially dependent whole-body hypersensitivity in rats: implications for extracephalic hypersensitivity in migraine.