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Todd J. Herron

Frankel Cardiovascular Regeneration Core Laboratory,
Cardiovascular Medicine-Internal Medicine,
Frankel Cardiovascular Regeneration Core Laboratory, Cardiovascular Medicine-Internal Medicine

University of Michigan, Ann Arbor

BIOGRAPHY

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PUBLICATIONS

Calcium-independent negative inotropy by beta-myosin heavy chain gene transfer in cardiac myocytes.

Circulation research Apr, 2007 | Pubmed ID: 17363698

Purkinje cell calcium dysregulation is the cellular mechanism that underlies catecholaminergic polymorphic ventricular tachycardia.

Heart rhythm Aug, 2010 | Pubmed ID: 20538074

Calcium and voltage mapping in hiPSC-CM monolayers.

Cell calcium Mar, 2016 | Pubmed ID: 26922095

Extracellular Matrix-Mediated Maturation of Human Pluripotent Stem Cell-Derived Cardiac Monolayer Structure and Electrophysiological Function.

Circulation. Arrhythmia and electrophysiology Apr, 2016 | Pubmed ID: 27069088

Deficient cMyBP-C protein expression during cardiomyocyte differentiation underlies human hypertrophic cardiomyopathy cellular phenotypes in disease specific human ES cell derived cardiomyocytes.

Journal of molecular and cellular cardiology Oct, 2016 | Pubmed ID: 27620334

hiPSC-CM Monolayer Maturation State Determines Drug Responsiveness in High Throughput Pro-Arrhythmia Screen.

Scientific reports Oct, 2017 | Pubmed ID: 29061979

Stiffness triggers non-coding RNA pathology.

Nature biomedical engineering Feb, 2019 | Pubmed ID: 30944436

Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations.

Regulatory toxicology and pharmacology : RTP , | Pubmed ID: 32822771

Human perinatal stem cell derived extracellular matrix enables rapid maturation of hiPSC-CM structural and functional phenotypes.

Scientific reports Nov, 2020 | Pubmed ID: 33149250

INSTITUTIONS

University of Michigan, Ann Arbor

JOVE ARTICLES

High-Throughput Cardiotoxicity Screening Using Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Monolayers

Andre Monteiro da Rocha¹,

Andrew Allan²,

Travis Block³,

Jeffery Creech¹,

Todd J. Herron¹

¹Frankel Cardiovascular Regeneration Core Laboratory, Cardiovascular Medicine-Internal Medicine, University of Michigan, Ann Arbor,

², CAIRN Research,

³, StemBioSys, Inc.

Bioengineering

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Todd J. Herron

Frankel Cardiovascular Regeneration Core Laboratory,Cardiovascular Medicine-Internal Medicine,Frankel Cardiovascular Regeneration Core Laboratory, Cardiovascular Medicine-Internal Medicine

University of Michigan, Ann Arbor

High-Throughput Cardiotoxicity Screening Using Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Monolayers

Frankel Cardiovascular Regeneration Core Laboratory,
Cardiovascular Medicine-Internal Medicine,
Frankel Cardiovascular Regeneration Core Laboratory, Cardiovascular Medicine-Internal Medicine