Pierre-Alain Clavien

Laparoscopic Roux-en-Y gastric bypass, but not rebanding, should be proposed as rescue procedure for patients with failed laparoscopic gastric banding.

A prospective randomized study in 100 consecutive patients undergoing major liver resection with versus without ischemic preconditioning.

Laparoscopic gastric bypass is superior to laparoscopic gastric banding for treatment of morbid obesity.

Novel short-term hypothermic oxygenated perfusion (HOPE) system prevents injury in rat liver graft from non-heart beating donor.

Hepatic steatosis is a risk factor for postoperative complications after major hepatectomy: a matched case-control study.

Immunologic ignorance of vascular endothelial cells expressing minor histocompatibility antigen.

A new journal devoted to patient safety in surgery: the time is now!

Redundant publications in surgery: a threat to patient safety?

Reconstruction of the gastric passage by a side-to-side gastrogastrostomy after failed vertical-banded gastroplasty: a case report.

Challenges in evaluating surgical innovation.

A lymphotoxin-driven pathway to hepatocellular carcinoma.

IFN-gamma-receptor signaling ameliorates transplant vasculopathy through attenuation of CD8+ T-cell-mediated injury of vascular endothelial cells.

Quality assessment in surgery: mission impossible?

Evaluation of Hepato-Pancreato-Biliary (HPB) fellowships: an international survey of programme directors.

Cosmesis and body image after single-port laparoscopic or conventional laparoscopic cholecystectomy: a multicenter double blinded randomised controlled trial (SPOCC-trial).

Recommendations for liver transplantation for hepatocellular carcinoma: an international consensus conference report.

Perception of surgical complications among patients, nurses and physicians: a prospective cross-sectional survey.

Laparoscopic gastric pouch and remnant resection: a novel approach to refractory anastomotic ulcers after Roux-en-Y gastric bypass: case report.

From abstract to impact in cardiovascular research: factors predicting publication and citation.

The 5th anniversary of "Patient Safety in Surgery" - from the Journal's origin to its future vision.

Does pharmacological conditioning with the volatile anaesthetic sevoflurane offer protection in liver surgery?

Ischemia/Reperfusion injury in liver surgery and transplantation.

Poor level of agreement on the management of postoperative pancreatic fistula: results of an international survey.

Multimodal treatment strategies in patients undergoing surgery for hepatocellular carcinoma.

Hypothermic oxygenated perfusion (HOPE) protects from biliary injury in a rodent model of DCD liver transplantation.

Reply to letter: "The balance of risk score for allocation in liver transplantation".

Nanomagnet-based removal of lead and digoxin from living rats.

Targeting quality in surgery.

The wealth of nations and the dissemination of cardiovascular research.

Successful Salvage Chemotherapy with FOLFIRINOX for Recurrent Mixed Acinar Cell Carcinoma and Ductal Adenocarcinoma of the Pancreas in an Adolescent Patient.

Novel rescue procedure for inferior vena cava reconstruction in living-donor liver transplantation using a vascular graft recovered 25 h after donors' circulatory death and systematic review.

HOPE for human liver grafts obtained from donors after cardiac death.

Small animal magnetic resonance imaging: an efficient tool to assess liver volume and intrahepatic vascular anatomy.

Management of anastomotic ulcers after Roux-en-Y gastric bypass: results of an international survey.

MMP-9 deficiency shelters endothelial PECAM-1 expression and enhances regeneration of steatotic livers after ischemia and reperfusion injury.

An independent jury-based consensus conference model for the development of recommendations in medico-surgical practice.

Managing multicentre clinical trials with open source.

Reply to letter: "accelerated liver hypertrophy: ALPPS and more!".

Platelet-derived serotonin: translational implications for liver regeneration.

Systemic protection through remote ischemic preconditioning is spread by platelet-dependent signaling in mice.

ALPPS offers a better chance of complete resection in patients with primarily unresectable liver tumors compared with conventional-staged hepatectomies: results of a multicenter analysis.

Fasting protects liver from ischemic injury through Sirt1-mediated downregulation of circulating HMGB1 in mice.

Reply to letter: "chemotherapy before liver resection of colorectal metastases: friend or foe?".

Warm vs. cold perfusion techniques to rescue rodent liver grafts.

Job satisfaction among chairs of surgery from Europe and North America.

Distinguishing infected from noninfected abdominal fluid collections after surgery: an imaging, clinical, and laboratory-based scoring system.

Challenges to liver transplantation and strategies to improve outcomes.

Hypothermic Oxygenated Perfusion (HOPE) downregulates the immune response in a rat model of liver transplantation.

Reply: To PMID 24277679.

Pheochromocytoma crisis.

Being a surgeon--the myth and the reality: a meta-synthesis of surgeons' perspectives about factors affecting their practice and well-being.

Early survival and safety of ALPPS: first report of the International ALPPS Registry.

Systematic review and meta-analysis of feasibility, safety, and efficacy of a novel procedure: associating liver partition and portal vein ligation for staged hepatectomy.

Reply to: "The rescue of DCD rodent livers grafts: is there HOPE?".

Is partial-ALPPS safer than ALPPS? A single-center experience.

ALPPS Offers a Better Chance of Complete Resection in Patients with Primarily Unresectable Liver Tumors. Results of a Multicentre Analysis: Reply.

Conditioning With Sevoflurane in Liver Transplantation: Results of a Multicenter Randomized Controlled Trial.

Leadership: ten tips for choosing an academic chair.

Reply to: the "Reply to Slankamenac et al's Comprehensive Complication Index Validation Study (November 2014)".

Ruptured hepatic artery after hepatectomy.

"A randomized, double-blind study of the effects of omega-3 fatty acids (Omegaven) on outcome after major liver resection".

Classification of Intraoperative Complications: Reply.

Is single portal vein approach sufficient for hypothermic machine perfusion of DCD liver grafts?

Cosmesis and Body Image in Patients Undergoing Single-port Versus Conventional Laparoscopic Cholecystectomy: A Multicenter Double-blinded Randomized Controlled Trial (SPOCC-trial).

Laparoscopic Living Donor Left Lateral Sectionectomy: A New Standard Practice for Donor Hepatectomy.

First Comparison of Hypothermic Oxygenated PErfusion Versus Static Cold Storage of Human Donation After Cardiac Death Liver Transplants: An International-matched Case Analysis.

Prediction of Mortality After ALPPS Stage-1: An Analysis of 320 Patients From the International ALPPS Registry.

Too Many Languages in the ALPPS: Preventing Another Tower of Babel?

Reply to 'Is single portal vein perfusion the best approach for machine preservation of liver grafts?'.

Selective portal vein injection for the design of syngeneic models of liver malignancy.

Constitutive androstane receptor (Car)-driven regeneration protects liver from failure following tissue loss.

In vivo risk evaluation of carbon-coated iron carbide nanoparticles based on short- and long-term exposure scenarios.

Modified associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure with right anterior liver sector congestion: Friend or foe?

Liver retransplantation with cavoportal hemitransposition after percutaneous mesocaval shunt creation.

Acute appendicitis in overweight patients: the role of preoperative imaging.

Reply to the Letter: Improving the Safety of ALPPS Procedure: The Optimal Compromise Between Drop-out and Mortality Risk? Comment on: Schadde E et al Prediction of Mortality After ALPPS Stage-1: An Analysis of 320 Patients From the International ALPPS Registry. Ann Surg. 2015;262: 780-786.

The ALPPS Risk Score: Avoiding Futile Use of ALPPS.

Reply to "Reducing Nonanastomotic Biliary Strictures in Donation After Circulatory Death Liver Transplantation: Cold Ischemia Matters".

Antihypoxic Potentiation of Standard Therapy for Experimental Colorectal Liver Metastasis through Myo-Inositol Trispyrophosphate.

Liver kinetic growth rate predicts postoperative liver failure after ALPPS.

Guidelines for Perioperative Care for Liver Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations.

Omega-3 Fatty Acids Protect Fatty and Lean Mouse Livers After Major Hepatectomy.

Remote Ischemic Preconditioning: A Novel Strategy in Rescuing Older Livers From Ischemia-reperfusion Injury in a Rodent Model.

Hypoxia-driven Hif2a coordinates mouse liver regeneration by coupling parenchymal growth to vascular expansion.

Silencing sirtuins: A novel way to thwart reperfusion injury?

Intraoperative adverse events during irreversible electroporation-a call for caution.

Development of OXY111A, a novel hypoxia-modifier as a potential antitumor agent in patients with hepato-pancreato-biliary neoplasms - Protocol of a first Ib/IIa clinical trial.

How much liver needs to be transected in ALPPS? A translational study investigating the concept of less invasiveness.

Patient Survival After Simultaneous ALPPS and Colorectal Resection.

Survival after associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) for advanced colorectal liver metastases: A case-matched comparison with palliative systemic therapy.

Neoadjuvant chemotherapy does not affect future liver remnant growth and outcomes of associating liver partition and portal vein ligation for staged hepatectomy.

Combination of Antiretroviral Drugs Zidovudine and Efavirenz Impairs Tumor Growths in a Mouse Model of Cancer.

Training in Minimally Invasive Pancreatic Resections: a paradigm shift away from "See one, Do one, Teach one".

Outcome of ALPPS for perihilar cholangiocarcinoma: case-control analysis including the first series from the international ALPPS registry.

Notice of concern regarding: Hypoxia of the growing liver accelerates regeneration.

Rapid liver volume increase induced by associating liver partition with portal vein ligation for staged hepatectomy (ALPPS): Is it edema, steatosis, or true proliferation?

Impact of postoperative complications on readmission and long-term survival in patients following surgery for colorectal cancer.

Temporary portal vein embolization is as efficient as permanent portal vein embolization in mice.

The Comprehensive Complication Index (CCI®): Added Value and Clinical Perspectives 3 Years "Down the Line".

Liver transplantation for colorectal liver metastasis: Survival without recurrence can be achieved.

The comprehensive complication index (CCI) is a more sensitive complication index than the conventional Clavien-Dindo classification in radical gastric cancer surgery.

Can immunosuppression be stopped after liver transplantation?

The Allosteric Hemoglobin Effector ITPP Inhibits Metastatic Colon Cancer in Mice.

Risk Adjustment in ALPPS Is Associated With a Dramatic Decrease in Early Mortality and Morbidity.

Advances in hypothermic perfusion.

Obituary for Christophe Mariette.

Hypothermic oxygenated perfusion (HOPE) for fatty liver grafts in rats and humans.

Treatment strategies and outcome of surgery for synchronous colorectal liver metastases.

Defining Benchmarks in Liver Transplantation: A Multicenter Outcome Analysis Determining Best Achievable Results.

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development.

ALPPS as a salvage procedure after insufficient future liver remnant hypertrophy following portal vein occlusion.

Liver resection for metastases not of colorectal, neuroendocrine, sarcomatous, or ovarian (NCNSO) origin: A multicentric study.

The Southampton Consensus Guidelines for Laparoscopic Liver Surgery: From Indication to Implementation.

Potentially inappropriate liver transplantation in the era of the "sickest first" policy - A search for the upper limits.

The Principle of Preserving Outflow Structures in Partial ALPPS: a commentary on "Segment 4: A Key Point of ALPPS Procedure".

"HEATPAC" - a phase II randomized study of concurrent thermochemoradiotherapy versus chemoradiotherapy alone in locally advanced pancreatic cancer.

Impact of associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) on growth of colorectal liver metastases.

The 10 anniversary of patient safety in surgery.

Adjuvant treatment of resectable biliary tract cancer with cisplatin plus gemcitabine: A prospective single center phase II study.

cHCC-CCA: Consensus terminology for primary liver carcinomas with both hepatocytic and cholangiocytic differentation.

Uploading cellular batteries: Caring for mitochondria is key.

Hepatic artery occlusion in liver transplantation: What counts more, the type of reconstruction or the severity of the recipient's disease?

Exogenous melatonin protects small-for-size liver grafts by promoting monocyte infiltration and releases interleukin-6.

When Shunts Erode-Duodenal Perforation by a Mesocaval Gore-Tex Shunt.

JNK1 induces hedgehog signaling from stellate cells to accelerate liver regeneration in mice.

10th Anniversary of ALPPS-Lessons Learned and quo Vadis.

Systematic review and meta-analysis of postoperative pancreatic fistula rates using the updated 2016 International Study Group Pancreatic Fistula definition in patients undergoing pancreatic resection with soft and hard pancreatic texture.

Perfusion settings and additives in liver normothermic machine perfusion with red blood cells as oxygen carrier. A systematic review of human and porcine perfusion protocols.

A systematic review and meta-analysis of rescue revascularization with arterial conduits in liver transplantation.

Novel Benefits of Remote Ischemic Preconditioning Through VEGF-dependent Protection From Resection-induced Liver Failure in the Mouse.

Reply to "Ex situ normothermic machine perfusion of donor livers using a haemoglobin-based oxygen carrier: a viable alternative to red blood cells".

Preoperative Evaluation of Pancreatic Fibrosis and Lipomatosis: Correlation of Magnetic Resonance Findings With Histology Using Magnetization Transfer Imaging and Multigradient Echo Magnetic Resonance Imaging.

Outcomes of DCD liver transplantation using organs treated by hypothermic oxygenated perfusion before implantation.

Performance validation of the ALPPS risk model.

The growing discrepancy between resident training in colonic surgery and the rising number of general surgery graduates.

Editorial comment: different perspectives on severity of postoperative morbidity.

Surgical Research in Patients: Ideal Time for an IDEAL Checklist.

Evolving Trends in Machine Perfusion for Liver Transplantation.

Yes-associated protein promotes early hepatocyte cell cycle progression in regenerating liver after tissue loss.

Hypothermic Oxygenated Perfusion: A Simple and Effective Method to Modulate the Immune Response in Kidney Transplantation.

MRI texture analysis for differentiation of malignant and benign hepatocellular tumors in the non-cirrhotic liver.

Benchmarks in Pancreatic Surgery: A Novel Tool for Unbiased Outcome Comparisons.

Dealing with insufficient liver remnant: Associating liver partition and portal vein ligation for staged hepatectomy.

Interprofessional and interdisciplinary collaboration for early phase oncological clinical trials in academia-Myo-inositoltrispyrophophate as model.

Pancreatectomy and body mass index: an international evaluation of cumulative postoperative complications using the comprehensive complications index.

Allocation of liver grafts worldwide - Is there a best system?

Improved Survival in Liver Transplant Patients Receiving Prolonged-release Tacrolimus-based Immunosuppression in the European Liver Transplant Registry (ELTR): An Extension Study.

Reply to: "Canadian liver transplant allocation for hepatocellular carcinoma".

ALPPS in neuroendocrine liver metastases not amenable for conventional resection - lessons learned from an interim analysis of the International ALPPS Registry.

Novel Real-time Prediction of Liver Graft Function During Hypothermic Oxygenated Machine Perfusion Before Liver Transplantation.

Defining Benchmark Outcomes for ALPPS.

Perioperative omega-3 fatty acids fail to confer protection in liver surgery: Results of a multicentric, double-blind, randomized controlled trial.

Procedural Surgical RCTs in Daily Practice: Do Surgeons Adopt Or Is It Just a Waste of Time?

The potential of machine learning to predict postoperative pancreatic fistula based on preoperative, non-contrast-enhanced CT: A proof-of-principle study.

Renal Impairment Is Associated with Reduced Outcome After Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy.

Ablation or Resection for Colorectal Liver Metastases? A Systematic Review of the Literature.

Exploration of the Transcriptional Landscape of ALPPS Reveals the Pathways of Accelerated Liver Regeneration.

S100A11/ANXA2 belongs to a tumour suppressor/oncogene network deregulated early with steatosis and involved in inflammation and hepatocellular carcinoma development.

An integrated perfusion machine preserves injured human livers for 1 week.

How to Handle Arterial Conduits in Liver Transplantation? Evidence From the First Multicenter Risk Analysis.

ALPPS for Locally Advanced Intrahepatic Cholangiocarcinoma: Did Aggressive Surgery Lead to the Oncological Benefit? An International Multi-center Study.

Hepatobiliary scintigraphy and kinetic growth rate predict liver failure after ALPPS: a multi-institutional study.

Frequency and causes of delayed diagnosis of visceral artery pseudoaneurysms with CT: Lessons learned.

How to Establish Benchmarks for Surgical Outcomes?: A Checklist Based on an International Expert Delphi Consensus.

The future of liver transplantation: an interview with Pierre-Alain Clavien.

Hepatic Vein Embolization for Safer Liver Surgery: Insignificant Novelty or a Breakthrough?

Modern therapeutic approaches for the treatment of malignant liver tumours.

Parastomal gallbladder herniation: A case report and review of the literature.

Hypothermic Oxygenated Perfusion Versus Normothermic Regional Perfusion in Liver Transplantation From Controlled Donation After Circulatory Death: First International Comparative Study.

Choices of Therapeutic Strategies for Colorectal Liver Metastases Among Expert Liver Surgeons: A Throw of the Dice?

First Long-term Oncologic Results of the ALPPS Procedure in a Large Cohort of Patients With Colorectal Liver Metastases.

Prospective validation of classification of intraoperative adverse events (ClassIntra): international, multicentre cohort study.

Defining Benchmark Outcomes for Pancreatoduodenectomy With Portomesenteric Venous Resection.

Hypothermic Oxygenated Liver Perfusion (HOPE) Prevents Tumor Recurrence in Liver Transplantation From Donation After Circulatory Death.

Can Early Postoperative Complications Predict High Morbidity and Decrease Failure to Rescue Following Major Abdominal Surgery?

Hypothermic oxygenated perfusion protects from mitochondrial injury before liver transplantation.

Response to the Comment on "Injury or Function-What Is Best to Assess Organ Viability Before Liver Graft Implantation?".

Reply to: Lactate measurements in an integrated perfusion machine for human livers.

Hyperoxia in portal vein causes enhanced vasoconstriction in arterial vascular bed.

A Call for Randomization in Clinical Trials of Liver Machine Perfusion Preservation.

Comment on "Making Every Liver Count Increased Transplant Yield of Donor Livers Through Normothermic Machine Perfusion".

Pancreatic fistulas following distal pancreatectomy are unrelated to the texture quality of the pancreas.

Bile formation in long-term ex situ perfused livers.

Tumor Oxygenation by Myo-Inositol Trispyrophosphate Enhances Radiation Response.

When transmigrates from the liver into the pericardium: a case report.

Proposal of a New Comprehensive Notation for Hepatectomy: The "New World" Terminology.

Multimodal treatment strategies for colorectal liver metastases.

Combination of HAI-FUDR and Systemic Gemcitabine and Cisplatin in Unresectable Cholangiocarcinoma: A Dose Finding Single Center Study.

Repeated hepatectomy after ALPPS for recurrence of colorectal liver metastasis: the edge of limits?

Nighttime Cholecystectomies are Safe When Controlled for Individual Patient Risk Factors-A Nationwide Case-Control Analysis.

Induction of liver hypertrophy for extended liver surgery and partial liver transplantation: State of the art of parenchyma augmentation-assisted liver surgery.

Liver metastases.

Sources and prevention of graft infection during long-term ex situ liver perfusion.

Demise of "Hilar En Bloc Resection by No-touch Technique" as Surgery for Perihilar Cholangiocarcinoma: Dissociation Between Theory and Practice.

Phase Ib dose-escalation study of the hypoxia-modifier Myo-inositol trispyrophosphate in patients with hepatopancreatobiliary tumors.

Synthesis of coagulation factors during long-term ex situ liver perfusion.

Early Allograft Dysfunction and Complications in DCD Liver Transplantation: Expert Consensus Statements From the International Liver Transplantation Society.

Defining Global Benchmarks in Elective Secondary Bariatric Surgery Comprising Conversional, Revisional, and Reversal Procedures.

Perihilar Cholangiocarcinoma - Novel Benchmark Values for Surgical and Oncological Outcomes From 24 Expert Centers.

Long-term Normothermic Machine Preservation of Partial Livers: First Experience With 21 Human Hemi-livers.

Neoadjuvant Therapy for Resectable Pancreatic Cancer: A New Standard of Care. Pooled Data From 3 Randomized Controlled Trials.

The Impact of Neoadjuvant Treatment on Survival in Patients Undergoing Pancreatoduodenectomy With Concomitant Portomesenteric Venous Resection: An International Multicenter Analysis.

A multicentre outcome analysis to define global benchmarks for donation after circulatory death liver transplantation.

Response to the Comment on: Demise of Hilar En Bloc Resection by No-touch Technique as Surgery for Perihilar Cholangiocarcinoma: Dissociation Between Theory and Practice.

Machine perfusion in liver transplantation.

Liver growth prediction in ALPPS - A multicenter analysis from the international ALPPS registry.

The essential requirements for an HPB centre to deliver high-quality outcomes.

Transplantation of a human liver following 3 days of ex situ normothermic preservation.

Low-dose aspirin confers protection against acute cellular allograft rejection after primary liver transplantation.

Robotic Distal Pancreatectomy, a Novel Standard of Care? Benchmark Values for Surgical Outcomes from 16 International Expert Centers.

Towards a Virtual "Global Academia of Surgeons".

Novel Benchmark Values for Redo Liver Transplantation: Does the Outcome Justify the Effort?

Liver Transplantation as a New Standard of Care in Patients With Perihilar Cholangiocarcinoma? Results From an International Benchmark Study.

Authors' response to 'Liver growth prediction in ALPPS-A multicenter analysis from the international ALPPS registry'.

An International Expert Delphi Consensus on Defining Textbook Outcome in Liver Surgery (TOLS).

Vascular injury during cholecystectomy: A multicenter critical analysis behind the drama.

Controversy Over Liver Transplantation or Resection for Neuroendocrine Liver Metastasis: Tumor Biology Cuts the Deal.

Benchmarks in colorectal surgery: multinational study to define quality thresholds in high and low anterior resection.

Observations and findings during the development of a subnormothermic/normothermic long-term ex vivo liver perfusion machine.

Safety and Efficacy of Robotic vs Open Liver Resection for Hepatocellular Carcinoma.

Long-term dynamic ex vivo organ preservation.

A multicenter randomized-controlled trial of hypothermic oxygenated perfusion (HOPE) for human liver grafts before transplantation.

Normalization of lipid oxidation defects arising from hypoxia early posthepatectomy prevents liver failure in mouse.

Hypoxia, a Targetable Culprit to Counter Pancreatic Cancer Resistance to Therapy.

Implementation and validation of a novel instrument for the grading of unexpected events in paediatric surgery: Clavien-Madadi classification.

Discussing Complications after Surgery Consists of Multiple Dimensions.

Revival of associating liver partition and portal vein ligation for staged hepatectomy for perihilar cholangiocarcinoma: An international multicenter study with promising outcomes.

FOLFIRINOX or Gemcitabine-based Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Cancer: A Multi-institutional, Patient-Level, Meta-analysis and Systematic Review.

Delivering Safe Surgical Care While Simultaneously Caring for Patients With COVID-19; Assessment of Patient Selection, Volume and Outcomes in a Tertiary Care Hospital.