Radhika Aramandla

Intraislet endothelial cells contribute to revascularization of transplanted pancreatic islets.

Enhanced expression of VEGF-A in β cells increases endothelial cell number but impairs islet morphogenesis and β cell proliferation.

Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes β cell regeneration.

Human islet preparations distributed for research exhibit a variety of insulin-secretory profiles.

Stress-impaired transcription factor expression and insulin secretion in transplanted human islets.

Development of a reliable automated screening system to identify small molecules and biologics that promote human β-cell regeneration.

α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes.

Cystic fibrosis-related diabetes is caused by islet loss and inflammation.

Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis.

Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks.

Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable.

Integrated human pseudoislet system and microfluidic platform demonstrate differences in GPCR signaling in islet cells.

SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells.

Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration.

Combinatorial transcription factor profiles predict mature and functional human islet α and β cells.

Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes.

Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss.

Exocrine pancreas in type 1 and type 2 diabetes: different patterns of fibrosis, metaplasia, angiopathy, and adiposity.