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Department of Biochemistry
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Succinate Can Shuttle Reducing Power from the Hypoxic Retina to the O-Rich Pigment Epithelium.
Cell reports May, 2020 | Pubmed ID: 32375026
Uncoupling proteins in the mitochondrial defense against oxidative stress.
Progress in retinal and eye research Jul, 2021 | Pubmed ID: 33422637
An Analysis of Metabolic Changes in the Retina and Retinal Pigment Epithelium of Aging Mice.
Investigative ophthalmology & visual science Nov, 2021 | Pubmed ID: 34797906
Monocarboxylate Transporter 1 (MCT1) Mediates Succinate Export in the Retina.
Investigative ophthalmology & visual science Apr, 2022 | Pubmed ID: 35363247
Succinate metabolism in the retinal pigment epithelium uncouples respiration from ATP synthesis.
Cell reports Jun, 2022 | Pubmed ID: 35675773
Transducin-Deficient Rod Photoreceptors Evaluated With Optical Coherence Tomography and Oxygen Consumption Rate Energy Biomarkers.
Investigative ophthalmology & visual science Dec, 2022 | Pubmed ID: 36576748
Aerobic Glycolysis in Photoreceptors Supports Energy Demand in the Absence of Mitochondrial Coupling.
Advances in experimental medicine and biology , 2023 | Pubmed ID: 37440069
University of Washington
Matthew K. Grumbine1,
Varun Kamat2,
Khang Bao1,
Trevor Crupi1,
Kedar Mokate2,
Rayne Lim3,
Jennifer R. Chao3,
Brian M. Robbings4,
Daniel T. Hass4,
James B. Hurley4,
Ian R. Sweet1,2
1, EnTox Sciences, Inc,
2UW Medicine Diabetes Institute, University of Washington,
3Department of Ophthalmology, University of Washington,
4Department of Biochemistry, University of Washington
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