Kazunori Nakajima

Cell and molecular mechanisms that control cortical layer formation in the brain.

Cellular and molecular mechanisms of neuronal migration in neocortical development.

Multipolar migration: the third mode of radial neuronal migration in the developing cerebral cortex.

Birth-date dependent alignment of GABAergic neurons occurs in a different pattern from that of non-GABAergic neurons in the developing mouse visual cortex.

Expression profiles of EphA3 at both the RNA and protein level in the developing mammalian forebrain.

Neuronal migration in cortical development.

Birth-date-dependent segregation of the mouse cerebral cortical neurons in reaggregation cultures.

The caudal migratory stream: a novel migratory stream of interneurons derived from the caudal ganglionic eminence in the developing mouse forebrain.

Switching of alpha-catenin from alphaE-catenin in the cortical ventricular zone to alphaN-catenin II in the intermediate zone.

Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development.

Mouse Disabled1 (DAB1) is a nucleocytoplasmic shuttling protein.

Expression profiles of Insulin-like growth factor binding protein-like 1 in the developing mouse forebrain.

Control of tangential/non-radial migration of neurons in the developing cerebral cortex.

Computational cell model based on autonomous cell movement regulated by cell-cell signalling successfully recapitulates the "inside and outside" pattern of cell sorting.

Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex.

Migratory behavior of presumptive interneurons is affected by AMPA receptor activation in slice cultures of embryonic mouse neocortex.

[Mechanisms of cerebral cortical development].

Labeling embryonic mouse central nervous system cells by in utero electroporation.

Cell-autonomous roles of ARX in cell proliferation and neuronal migration during corticogenesis.

The cortical subventricular zone-specific molecule Svet1 is part of the nuclear RNA coded by the putative netrin receptor gene Unc5d and is expressed in multipolar migrating cells.

Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses.

COUP-TFII is preferentially expressed in the caudal ganglionic eminence and is involved in the caudal migratory stream.

Differences of migratory behavior between direct progeny of apical progenitors and basal progenitors in the developing cerebral cortex.

Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1.

Downregulation of functional Reelin receptors in projection neurons implies that primary Reelin action occurs at early/premigratory stages.

Role of dual leucine zipper-bearing kinase (DLK/MUK/ZPK) in axonal growth.

Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits.

Ectopic Reelin induces neuronal aggregation with a normal birthdate-dependent "inside-out" alignment in the developing neocortex.

Rab GTPases-dependent endocytic pathways regulate neuronal migration and maturation through N-cadherin trafficking.

Migration defects by DISC1 knockdown in C57BL/6, 129X1/SvJ, and ICR strains via in utero gene transfer and virus-mediated RNAi.

Neural crest-derived stem cells migrate and differentiate into cardiomyocytes after myocardial infarction.

Cellular composition and organization of the subventricular zone and rostral migratory stream in the adult and neonatal common marmoset brain.

Regulation of cortical neuron migration by the Reelin signaling pathway.

DISC1-dependent switch from progenitor proliferation to migration in the developing cortex.

Changes in cortical interneuron migration contribute to the evolution of the neocortex.

Disrupted-in-Schizophrenia-1 (Disc1) is necessary for migration of the pyramidal neurons during mouse hippocampal development.

PDK1-Foxo1 in agouti-related peptide neurons regulates energy homeostasis by modulating food intake and energy expenditure.

The outermost region of the developing cortical plate is crucial for both the switch of the radial migration mode and the Dab1-dependent "inside-out" lamination in the neocortex.

[What does Reelin control to regulate neuronal layer formation in the developing cerebral cortex?].

GABAergic precursor transplantation into the prefrontal cortex prevents phencyclidine-induced cognitive deficits.

N-cadherin regulates radial glial fiber-dependent migration of cortical locomoting neurons.

Segregation and pathfinding of callosal axons through EphA3 signaling.

GABAergic interneuron migration and the evolution of the neocortex.

Leucine-rich glioma inactivated 1 (Lgi1), an epilepsy-related secreted protein, has a nuclear localization signal and localizes to both the cytoplasm and the nucleus of the caudal ganglionic eminence neurons.

Migratory pathways of GABAergic interneurons when they enter the neocortex.

A phosphatidylinositol lipids system, lamellipodin, and Ena/VASP regulate dynamic morphology of multipolar migrating cells in the developing cerebral cortex.

Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1.

DISC1: a key lead in studying cortical development and associated brain disorders.

[Neuronal distribution in the cerebral cortex and its significance in schizophrenia].

Cdk5 phosphorylation of ErbB4 is required for tangential migration of cortical interneurons.

Hippocampal pyramidal neurons switch from a multipolar migration mode to a novel "climbing" migration mode during development.

Time-lapse imaging of cell cycle dynamics during development in living cardiomyocyte.

How does Reelin control neuronal migration and layer formation in the developing mammalian neocortex?

Cdk5 and its substrates, Dcx and p27kip1, regulate cytoplasmic dilation formation and nuclear elongation in migrating neurons.

Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex.

Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS.

Reelin has a preventive effect on phencyclidine-induced cognitive and sensory-motor gating deficits.

Importance of Reelin C-terminal region in the development and maintenance of the postnatal cerebral cortex and its regulation by specific proteolysis.

Cellular dynamics of neuronal migration in the hippocampus.

Analysis of cardiomyocyte movement in the developing murine heart.

Proper Level of Cytosolic Disabled-1, Which Is Regulated by Dual Nuclear Translocation Pathways, Is Important for Cortical Neuronal Migration.

The COUP-TFII/Neuropilin-2 is a molecular switch steering diencephalon-derived GABAergic neurons in the developing mouse brain.

Neuronal Heterotopias Affect the Activities of Distant Brain Areas and Lead to Behavioral Deficits.

Developmental origin of abnormal dendritic growth in the mouse brain induced by in utero disruption of aryl hydrocarbon receptor signaling.

In Utero Bisphenol A Exposure Induces Abnormal Neuronal Migration in the Cerebral Cortex of Mice.

Identity of neocortical layer 4 neurons is specified through correct positioning into the cortex.

Mutually repressive interaction between Brn1/2 and Rorb contributes to the establishment of neocortical layer 2/3 and layer 4.

PDK1-Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex.

Editorial: Mechanisms of Neuronal Migration during Corticogenesis.

The mitotic tensegrity guardian tau protects mammary epithelia from katanin-like1-induced aneuploidy.

[Role of Reelin during Layer Formation in the Cerebral Neocortex].

SUMOylation of DISC1: a potential role in neural progenitor proliferation in the developing cortex.

DISC1 a key molecular lead in psychiatry and neurodevelopment: No-More Disrupted-in-Schizophrenia 1.

ADP Ribosylation Factor 6 Regulates Neuronal Migration in the Developing Cerebral Cortex through FIP3/Arfophilin-1-dependent Endosomal Trafficking of N-cadherin.

Reelin and Neuropsychiatric Disorders.

ApoER2 Controls Not Only Neuronal Migration in the Intermediate Zone But Also Termination of Migration in the Developing Cerebral Cortex.

Reelin transiently promotes N-cadherin-dependent neuronal adhesion during mouse cortical development.

A crossroad of neuronal diversity to build circuitry.

Association of impaired neuronal migration with cognitive deficits in extremely preterm infants.

Impaired dendritic growth and positioning of cortical pyramidal neurons by activation of aryl hydrocarbon receptor signaling in the developing mouse.

Enhanced expression of Pafah1b1 causes over-migration of cerebral cortical neurons into the marginal zone.

Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma.

CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations.

Subtype Specification of Cerebral Cortical Neurons in Their Immature Stages.

Drebrin-like (Dbnl) Controls Neuronal Migration via Regulating N-Cadherin Expression in the Developing Cerebral Cortex.

Both excitatory and inhibitory neurons transiently form clusters at the outermost region of the developing mammalian cerebral neocortex.

Timing and shaping mechanisms of neural development.

Role of the Immune System in the Development of the Central Nervous System.

Neuron-derived VEGF contributes to cortical and hippocampal development independently of VEGFR1/2-mediated neurotrophism.

VLDLR is not essential for reelin-induced neuronal aggregation but suppresses neuronal invasion into the marginal zone.

Two-Photon Voltage Imaging of Spontaneous Activity from Multiple Neurons Reveals Network Activity in Brain Tissue.

The Secreted Glycoprotein Reelin Suppresses the Proliferation and Regulates the Distribution of Oligodendrocyte Progenitor Cells in the Embryonic Neocortex.

Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner.

Comprehensive characterization of migration profiles of murine cerebral cortical neurons during development using FlashTag labeling.

Rhythmic activation of excitatory neurons in the mouse frontal cortex improves the prefrontal cortex-mediated cognitive function.

Dab1-deficient deep layer neurons prevent Dab1-deficient superficial layer neurons from entering the cortical plate.

Development of intensiometric indicators for visualizing N-cadherin interaction across cells.

Erratic and blood vessel-guided migration of astrocyte progenitors in the cerebral cortex.

Activation of Sonic Hedgehog Signaling Promotes Differentiation of Cortical Layer 4 Neurons via Regulation of Their Cell Positioning.

A Unique "Reversed" Migration of Neurons in the Developing Claustrum.

Heterozygous Null Mutation Disrupts Neocortical and Hippocampal Development.

Migratory mode transition of astrocyte progenitors in the cerebral cortex: an intrinsic or extrinsic cell process?

Interactions between neural cells and blood vessels in central nervous system development.