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Melanie Kirkby

Biologic and Radiopharmaceutical Drugs Directorate

BIOGRAPHY

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PUBLICATIONS

The Potential of Hormonal Therapies for Treatment of Triple-Negative Breast Cancer.

Cancers Sep, 2023 | Pubmed ID: 37835396

Targeting CD73 with flavonoids inhibits cancer stem cells and increases lymphocyte infiltration in a triple-negative breast cancer mouse model.

Frontiers in immunology , 2024 | Pubmed ID: 38601156

Evaluation of resazurin phenoxazine dye as a highly sensitive cell viability potency assay for natural killer cell-derived extracellular vesicle-based cancer biotherapeutics.

Journal of extracellular biology Jul, 2024 | Pubmed ID: 39022723

INSTITUTIONS

Biologic and Radiopharmaceutical Drugs Directorate

University of Ottawa

JOVE ARTICLES

Scalable Biomanufacturing Workflow to Produce and Isolate Natural Killer Cell-Derived Extracellular Vesicle-Based Cancer Biotherapeutics

Frederic St-Denis-Bissonnette^*,1,2,

Melanie Kirkby^*,1,2,

Lisheng Wang^2,3,4,

Jessie R. Lavoie^1,2

¹, Biologic and Radiopharmaceutical Drugs Directorate,

²Department of Biochemistry, Microbiology and Immunology Institute, University of Ottawa,

³Centre for Infection, Immunity and Inflammation Institute, University of Ottawa,

⁴Regenerative Medicine Program, Ottawa Hospital Research Institute

Cancer Research

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