Simon A. Gayther

Contribution of BRCA1 and BRCA2 mutations to inherited ovarian cancer.

Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer.

BRCA1 and BRCA2 mutations in a population-based study of male breast cancer.

Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene.

BRCA1/2 mutation status influences somatic genetic progression in inherited and sporadic epithelial ovarian cancer cases.

Histopathology, FIGO stage, and BRCA mutation status of ovarian cancers from the Gilda Radner Familial Ovarian Cancer Registry.

A modified medium that significantly improves the growth of human normal ovarian surface epithelial (OSE) cells in vitro.

STK15 polymorphisms and association with risk of invasive ovarian cancer.

A molecular genetic and statistical approach for the diagnosis of dual-site cancers.

Common variants in mismatch repair genes and risk of invasive ovarian cancer.

Ovarian cancer aetiology: facts and fiction.

Common variants in RB1 gene and risk of invasive ovarian cancer.

Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer.

Screening for the BRCA1-ins6kbEx13 mutation: potential for misdiagnosis. Mutation in brief #964. Online.

Association between single-nucleotide polymorphisms in hormone metabolism and DNA repair genes and epithelial ovarian cancer: results from two Australian studies and an additional validation set.

Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival.

A Perl toolkit for LIMS development.

A suite of Perl modules for handling microarray data.

Consortium analysis of 7 candidate SNPs for ovarian cancer.

BRCA1 and BRCA2 mutation prevalence and clinical characteristics of a population-based series of ovarian cancer cases from Denmark.

Multiple loci with different cancer specificities within the 8q24 gene desert.

Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients.

The effects of common genetic variants in oncogenes on ovarian cancer survival.

Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer.

Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer.

Chromosomes 6 and 18 induce neoplastic suppression in epithelial ovarian cancer cells.

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.

The clonal evolution of metastases from primary serous epithelial ovarian cancers.

Ovarian cancer: a clinical challenge that needs some basic answers.

Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.

Risk of ovarian cancer in women with first-degree relatives with cancer.

Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival.

Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer.

Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study.

The contribution of BRCA1 and BRCA2 to ovarian cancer.

Association between common germline genetic variation in 94 candidate genes or regions and risks of invasive epithelial ovarian cancer.

Eligibility for magnetic resonance imaging screening in the United Kingdom: effect of strict selection criteria and anonymous DNA testing on breast cancer incidence in the MARIBS Study.

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.

Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study.

An epigenetic signature in peripheral blood predicts active ovarian cancer.

ESR1/SYNE1 polymorphism and invasive epithelial ovarian cancer risk: an Ovarian Cancer Association Consortium study.

Polymorphism in the GALNT1 gene and epithelial ovarian cancer in non-Hispanic white women: the Ovarian Cancer Association Consortium.

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.

Senescent fibroblasts promote neoplastic transformation of partially transformed ovarian epithelial cells in a three-dimensional model of early stage ovarian cancer.

The inherited genetics of ovarian and endometrial cancer.

Vitamin D receptor rs2228570 polymorphism and invasive ovarian carcinoma risk: pooled analysis in five studies within the Ovarian Cancer Association Consortium.

Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium.

Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".

Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer.

Microcell-mediated chromosome transfer identifies EPB41L3 as a functional suppressor of epithelial ovarian cancers.

Progesterone receptor gene polymorphisms and risk of endometriosis: results from an international collaborative effort.

Vascular endothelial growth factor gene polymorphisms and ovarian cancer survival.

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population.

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

Common variants at 19p13 are associated with susceptibility to ovarian cancer.

Recruitment of newly diagnosed ovarian cancer patients proved challenging in a multicentre biobanking study.

Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers.

Profiling signatures of ovarian cancer tumour suppression using 2D-DIGE and 2D-LC-MS/MS with tandem mass tagging.

Cancer stem cells and epithelial ovarian cancer.

The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing.

Prostate cancer susceptibility polymorphism rs2660753 is not associated with invasive ovarian cancer.

Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk.

A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival.

LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer.

A polymorphism in the GALNT2 gene and ovarian cancer risk in four population based case-control studies.

Principles for the post-GWAS functional characterization of cancer risk loci.

MicroRNA processing and binding site polymorphisms are not replicated in the Ovarian Cancer Association Consortium.

Polymorphisms in stromal genes and susceptibility to serous epithelial ovarian cancer: a report from the Ovarian Cancer Association Consortium.

Estrogen receptor beta rs1271572 polymorphism and invasive ovarian carcinoma risk: pooled analysis within the Ovarian Cancer Association Consortium.

Modelling genetic and clinical heterogeneity in epithelial ovarian cancers.

Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers.

Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers.

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers.

Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer.

Ovarian cancer risk associated with inherited inflammation-related variants.

Gene set analysis of survival following ovarian cancer implicates macrolide binding and intracellular signaling genes.

Role of common genetic variants in ovarian cancer susceptibility and outcome: progress to date from the ovarian cancer association consortium (OCAC).

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers.

Common Variants at the 19p13.1 and ZNF365 Loci Are Associated with ER Subtypes of Breast Cancer and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.

Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies.

Common Breast Cancer Susceptibility Variants in LSP1 and RAD51L1 Are Associated with Mammographic Density Measures that Predict Breast Cancer Risk.

Inherited risk of ovarian cancer and the implications for screening.

Genome-Wide Association Study for Ovarian Cancer Susceptibility Using Pooled DNA.