Cancer Institute
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NEDD9 depletion destabilizes Aurora A kinase and heightens the efficacy of Aurora A inhibitors: implications for treatment of metastatic solid tumors.
Cancer research May, 2013 | Pubmed ID: 23539442
NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis.
Molecular cancer research : MCR Jan, 2014 | Pubmed ID: 24202705
NEDD9 regulates actin dynamics through cortactin deacetylation in an AURKA/HDAC6-dependent manner.
Molecular cancer research : MCR May, 2014 | Pubmed ID: 24574519
NEDD9/Arf6-dependent endocytic trafficking of matrix metalloproteinase 14: a novel mechanism for blocking mesenchymal cell invasion and metastasis of breast cancer.
Oncogene Jul, 2015 | Pubmed ID: 25241893
Prometastatic NEDD9 Regulates Individual Cell Migration via Caveolin-1-Dependent Trafficking of Integrins.
Molecular cancer research : MCR Mar, 2015 | Pubmed ID: 25319010
AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis.
Oncotarget Aug, 2015 | Pubmed ID: 26079538
Combination of Eribulin and Aurora A Inhibitor MLN8237 Prevents Metastatic Colonization and Induces Cytotoxic Autophagy in Breast Cancer.
Molecular cancer therapeutics Aug, 2016 | Pubmed ID: 27235164
Dual Targeting of Mesenchymal and Amoeboid Motility Hinders Metastatic Behavior.
Molecular cancer research : MCR Jun, 2017 | Pubmed ID: 28235899
LPA signaling is regulated through the primary cilium: a novel target in glioblastoma.
Oncogene Mar, 2018 | Pubmed ID: 29321663
Human Breast Cancer Xenograft Model Implicates Peroxisome Proliferator-activated Receptor Signaling as Driver of Cancer-induced Muscle Fatigue.
Clinical cancer research : an official journal of the American Association for Cancer Research Apr, 2019 | Pubmed ID: 30559167
Skeletal muscle reprogramming by breast cancer regardless of treatment history or tumor molecular subtype.
NPJ breast cancer , 2020 | Pubmed ID: 32550263
Nuclear Aurora-A kinase-induced hypoxia signaling drives early dissemination and metastasis in breast cancer: implications for detection of metastatic tumors.
Oncogene Sep, 2021 | Pubmed ID: 34326467
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