Department of Internal Medicine
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Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency.
Brain research Mar, 2012 | Pubmed ID: 22364637
BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development.
Developmental cell Apr, 2003 | Pubmed ID: 12689595
Modulation of mitochondrial function by endogenous Zn2+ pools.
Proceedings of the National Academy of Sciences of the United States of America May, 2003 | Pubmed ID: 12724524
Modulation of synaptic transmission by the BCL-2 family protein BCL-xL.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2003 | Pubmed ID: 12968005
Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2004 | Pubmed ID: 15342906
Exposure to hypoxia rapidly induces mitochondrial channel activity within a living synapse.
The Journal of biological chemistry Feb, 2005 | Pubmed ID: 15561723
Oligomeric Bax is a component of the putative cytochrome c release channel MAC, mitochondrial apoptosis-induced channel.
Molecular biology of the cell May, 2005 | Pubmed ID: 15772159
Actions of BAX on mitochondrial channel activity and on synaptic transmission.
Antioxidants & redox signaling Sep-Oct, 2005 | Pubmed ID: 16115013
The role of the mitochondrial apoptosis induced channel MAC in cytochrome c release.
Journal of bioenergetics and biomembranes Jun, 2005 | Pubmed ID: 16167172
Zinc-dependent multi-conductance channel activity in mitochondria isolated from ischemic brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2006 | Pubmed ID: 16793892
Hypoxia increases BK channel activity in the inner mitochondrial membrane.
Biochemical and biophysical research communications Jun, 2007 | Pubmed ID: 17481584
Expression of the voltage-gated sodium channel NaV1.5 in the macrophage late endosome regulates endosomal acidification.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2007 | Pubmed ID: 17548620
Bcl-xL inhibitor ABT-737 reveals a dual role for Bcl-xL in synaptic transmission.
Journal of neurophysiology Mar, 2008 | Pubmed ID: 18160428
Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2008 | Pubmed ID: 18250306
PKC-induced intracellular trafficking of Ca(V)2 precedes its rapid recruitment to the plasma membrane.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2008 | Pubmed ID: 18322103
Ischemic preconditioning blocks BAD translocation, Bcl-xL cleavage, and large channel activity in mitochondria of postischemic hippocampal neurons.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2008 | Pubmed ID: 18347331
Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons.
The Journal of cell biology Mar, 2009 | Pubmed ID: 19255249
Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase.
Nature cell biology Oct, 2011 | Pubmed ID: 21926988
Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential.
The Journal of cell biology Oct, 2011 | Pubmed ID: 21987637
N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death.
Nature neuroscience Apr, 2012 | Pubmed ID: 22366758
NAD kinase regulates the size of the NADPH pool and insulin secretion in pancreatic β-cells.
American journal of physiology. Endocrinology and metabolism Jul, 2012 | Pubmed ID: 22550069
Multipolar functions of BCL-2 proteins link energetics to apoptosis.
Trends in cell biology Jun, 2012 | Pubmed ID: 22560661
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