Mark Kindy

Apolipoprotein E modulates Alzheimer's Abeta(1-42)-induced oxidative damage to synaptosomes in an allele-specific manner.

Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis.

Apolipoprotein Serum Amyloid A in Alzheimer's Disease.

Abeta deposition is essential to AD neuropathology.

Apolipoprotein E and Alzheimer's disease: the protective effects of ApoE2 and E3.

Overexpression of SR-BI by adenoviral vector promotes clearance of apoA-I, but not apoB, in human apoB transgenic mice.

The fate of HDL particles in vivo after SR-BI-mediated selective lipid uptake.

Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome.

Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.

Fibroblast growth factor-18 reduced infarct volumes and behavioral deficits after transient occlusion of the middle cerebral artery in rats.

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain.

In vitro and in vivo modulations of benzo[c]phenanthrene-DNA adducts by DNA mismatch repair system.

Time window of fibroblast growth factor-18-mediated neuroprotection after occlusion of the middle cerebral artery in rats.

Neprilysin regulates amyloid Beta peptide levels.

Cholesterol and Alzheimer's disease: clinical and experimental models suggest interactions of different genetic, dietary and environmental risk factors.

Activation of nuclear factor kappaB In vivo selectively protects the murine small intestine against ionizing radiation-induced damage.

RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice.

Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene.

Establishment of epidermal cell lines derived from the skin of the Atlantic bottlenose dolphin (Tursiops truncatus).

Differential modulation of estrogen receptors (ERs) in ischemic brain injury: a role for ERalpha in estradiol-mediated protection against delayed cell death.

Complement-dependent P-selectin expression and injury following ischemic stroke.

A dolphin peripheral blood leukocyte cDNA microarray for studies of immune function and stress reactions.

Estradiol enhances neurogenesis following ischemic stroke through estrogen receptors alpha and beta.

Cysteine protease inhibitors effectively reduce in vivo levels of brain beta-amyloid related to Alzheimer's disease.

Neprilysin protects neurons against Abeta peptide toxicity.

JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction.

Semi-allogeneic vaccine for T-cell lymphoma.

Cysteine protease inhibitors reduce brain beta-amyloid and beta-secretase activity in vivo and are potential Alzheimer's disease therapeutics.

Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein.

Delta 2-specific opioid receptor agonist and hibernating woodchuck plasma fraction provide ischemic neuroprotection.

Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease.

High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice.

The dual role of tumor necrosis factor-alpha in the pathophysiology of spinal cord injury.

Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity.

Motoneuronotrophic factor analog GM6 reduces infarct volume and behavioral deficits following transient ischemia in the mouse.

Focal cerebral ischemia in the TNFalpha-transgenic rat.

Regeneration and characterization of adult mouse hippocampal neurons in a defined in vitro system.

Semi-allogeneic vaccines and tumor-induced immune tolerance.

GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism.

Magnesium chloride in a polyethylene glycol formulation as a neuroprotective therapy for acute spinal cord injury: preclinical refinement and optimization.

The vitamin D3 transcriptomic response in skin cells derived from the Atlantic bottlenose dolphin.

Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein.

The impact of methylmercury on 1,25-dihydroxyvitamin D3-induced transcriptomic responses in dolphin skin cells.

A new target for amyloid beta toxicity validated by standard and high-throughput electrophysiology.

Effective post-insult neuroprotection by a novel Ca(2+)/ calmodulin-dependent protein kinase II (CaMKII) inhibitor.

Pharmacogenetic features of cathepsin B inhibitors that improve memory deficit and reduce beta-amyloid related to Alzheimer's disease.

The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury.

Transcranial laser therapy attenuates amyloid-β peptide neuropathology in amyloid-β protein precursor transgenic mice.

Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis.

Targets for AD treatment: conflicting messages from γ-secretase inhibitors.

Vitamin D3-enriched diet correlates with a decrease of amyloid plaques in the brain of AβPP transgenic mice.

The cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activity.

Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease.

Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in mice.

Protective effects of incensole acetate on cerebral ischemic injury.

Deletion of the Cathepsin B Gene Improves Memory Deficits in a Transgenic Alzheimer's Disease Mouse Model Expressing AβPP Containing the Wild-Type β-Secretase Site Sequence.

Spinal cord infarction associated with subarachnoid hemorrhage.

Vitamin D3 supplementation at 4000 international units per day for one year results in a decrease of positive cores at repeat biopsy in subjects with low-risk prostate cancer under active surveillance.

Vitamin D3 supplementation (4000 IU/d for 1 y) eliminates differences in circulating 25-hydroxyvitamin D between African American and white men.

Expression of mRNAs for PPT, CGRP, NF-200, and MAP-2 in cocultures of dissociated DRG neurons and skeletal muscle cells in administration of NGF or NT-3.

The alternative complement pathway propagates inflammation and injury in murine ischemic stroke.

Vitamin D3 supplementation, low-risk prostate cancer, and health disparities.

Nanoparticles for targeted delivery of antioxidant enzymes to the brain after cerebral ischemia and reperfusion injury.

Biomaterial-based interventions for neuronal regeneration and functional recovery in rodent model of spinal cord injury: a systematic review.

Spinal cord injury: How can we improve the classification and quantification of its severity and prognosis?

A therapeutic cancer vaccine against GL261 murine glioma.

The Effect of Diet on Improved Endurance in Male C57BL/6 Mice.

Impact of nutrition on inflammation, tauopathy, and behavioral outcomes from chronic traumatic encephalopathy.