Pierluigi Castellone

Reversal of gastric electrical dysrhythmias by cisapride in children with functional dyspepsia. Report of three cases.

Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival.

Akt/protein kinase B promotes survival and hormone-independent proliferation of thyroid cells in the absence of dedifferentiating and transforming effects.

RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho.

Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenes.

Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2).

Genetic alterations in differentiated thyroid cancer: what can be expected for gene expression profiling of thyroid carcinomas.

Identification of H-Ras, RhoA, Rac1 and Cdc42 responsive genes.

Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase.

Tyrosine kinase oncoprotein, RET/PTC3, induces the secretion of myeloid growth and chemotactic factors.

Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cells.

Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas.

Anatomic variations due to radical prostatectomy. Impact on target volume definition and dose-volume parameters of rectum and bladder.

Chimeric G alpha i2/G alpha 13 proteins reveal the structural requirements for the binding and activation of the RGS-like (RGL)-containing Rho guanine nucleotide exchange factors (GEFs) by G alpha 13.

Autocrine activation of an osteopontin-CD44-Rac pathway enhances invasion and transformation by H-RasV12.

Multi-modal medical image integration to optimize radiotherapy planning in lung cancer treatment.

Rectal and bladder motion during conformal radiotherapy after radical prostatectomy.

The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells.

Target delineation in post-operative radiotherapy of brain gliomas: interobserver variability and impact of image registration of MR(pre-operative) images on treatment planning CT scans.

Osteopontin is overexpressed in human papillary thyroid carcinomas and enhances thyroid carcinoma cell invasiveness.

Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1.

Feasibility of [18F]FDG-PET and coregistered CT on clinical target volume definition of advanced non-small cell lung cancer.

Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis.

Overexpression of the cytokine osteopontin identifies aggressive laryngeal squamous cell carcinomas and enhances carcinoma cell proliferation and invasiveness.

Robo4 signaling in endothelial cells implies attraction guidance mechanisms.

Gene expression changes in a patient presenting nonleukaemic nasal granulocytic sarcoma to acute myelogenous leukaemia using 40 K cDNA microarray.

Cyclooxygenase-2 and colorectal cancer chemoprevention: the beta-catenin connection.

RET/papillary thyroid carcinoma oncogenic signaling through the Rap1 small GTPase.

Rac inhibits thrombin-induced Rho activation: evidence of a Pak-dependent GTPase crosstalk.

Role of computed tomography and [18F] fluorodeoxyglucose positron emission tomography image fusion in conformal radiotherapy of non-small cell lung cancer: a comparison with standard techniques with and without elective nodal irradiation.

A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma.

OPN/CD44v6 overexpression in laryngeal dysplasia and correlation with clinical outcome.

Biological role and potential therapeutic targeting of the chemokine receptor CXCR4 in undifferentiated thyroid cancer.

Dysregulated RET signaling in thyroid cancer.

Receptor tyrosine kinase inhibitors in thyroid cancer.

Extracellular superoxide dismutase is a growth regulatory mediator of tissue injury recovery.

The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation.

Laboratory assessment of factor VIII inhibitor titer: the North American Specialized Coagulation Laboratory Association experience.

SOD3 reduces inflammatory cell migration by regulating adhesion molecule and cytokine expression.

Diffraction imaging of spheres and melanoma cells with a microscope objective.

Thyroid cancer and inflammation.

Human embryonic stem cell-derived mesenchymal stromal cell transplantation in a rat hind limb injury model.

A novel de novo germ-line V292M mutation in the extracellular region of RET in a patient with phaeochromocytoma and medullary thyroid carcinoma: functional characterization.

Laboratory monitoring of new anticoagulants.

Extracellular superoxide dismutase is a thyroid differentiation marker down-regulated in cancer.

Von Willebrand factor assay proficiency testing. The North American Specialized Coagulation Laboratory Association experience.

SOD3 decreases ischemic injury derived apoptosis through phosphorylation of Erk1/2, Akt, and FoxO3a.

Inhibition of tumor cell migration and metastasis by the proton-sensing GPR4 receptor.

CD44 proteolysis increases CREB phosphorylation and sustains proliferation of thyroid cancer cells.

Biomarkers in thyroid tumor research: new diagnostic tools and potential targets of molecular-based therapy.

FOXM1 is a molecular determinant of the mitogenic and invasive phenotype of anaplastic thyroid carcinoma.

Brief report: mesenchymal stromal cell atrophy in coculture increases aggressiveness of transformed cells.