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UNIFAL-MG

1 ARTICLES PUBLISHED IN JoVE

Neuroscience

Ravena Carolina de Carvalho¹, Ana Laura Silva¹, Danielle Cavalcante de Paula¹, Laura Pereira Generoso¹, Natalie Lange Candido¹, Maria Gabriela Maziero Capello¹, Gabrielly Santos Pereira¹, Carlos Marcelo de Barros^1,2, Danielle Mazetto Cadide^1,2, Josie Resende Torres da Silva¹, Marcelo Lourenço da Silva¹

¹Laboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), UNIFAL-MG, ²SINPAIN Faculty

Here, we present a concise protocol for creating a preterm rat model, facilitating research on early postnatal pain management. The method involves performing a cesarean section three days before the expected birth, extracting preterm rat pups via hysterectomy, and integrating them with the biological offspring of a surrogate dam.