A Streamlined Approach for Mass Spectrometry-Based Proteomics Using Selected Tissue RegionsDongyoon Shin 1,2, Dayeon Lee 1, Young June Jeon 1, Kyoungbun Lee 3, Youngsoo Kim 2, Junho Park 1,2
1Department of Medical Science, School of Medicine, CHA University, 2Department of Proteomic Research, CHA Future Medicine Research Institute, 3Department of Pathology, Seoul National University Hospital
Here, we establish a mass spectrometry-based proteomic method using isolated regions of interest in formalin-fixed, paraffin-embedded tissue sections. This protocol is used to analyze proteome from specific tissue areas in archived formalin-fixed, paraffin-embedded tissue sections.
