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Georgia Regents University

3 ARTICLES PUBLISHED IN JoVE

Medicine

Assessing Myogenic Response and Vasoactivity In Resistance Mesenteric Arteries Using Pressure Myography

Ravirajsinh N. Jadeja¹, Vikrant Rachakonda², Zsolt Bagi³, Sandeep Khurana¹

¹Section of Gastroenterology and Hepatology, Georgia Regents University, ²Division of Gastroenterology and Hepatology, University of Pittsburgh School of Medicine, ³Vascular Biology Center, Georgia Regents University

Pressure myography is used to assess vasoactivity of small arteries that develop sustained constriction when pressurized. This manuscript provides a detailed protocol to assess in isolated segments of small mesenteric arteries from rats, vasoactivity and the effect of intraluminal pressure on vascular diameter.

Medicine

Coordinate Mapping of Hyolaryngeal Mechanics in Swallowing

Thomas Z. Thompson¹, Farres Obeidin¹, Alisa A. Davidoff², Cody L. Hightower¹, Christohper Z. Johnson¹, Sonya L. Rice¹, Rebecca-Lyn Sokolove¹, Brandon K. Taylor¹, John M. Tuck¹, William G. Pearson, Jr.^3,4

¹Medical College of Georgia, Georgia Regents University, ²Department of Communicative Sciences and Disorders, New York University, ³Department of Cellular Biology & Anatomy, Georgia Regents University, ⁴Department of Otolaryngology, Georgia Regents University

Coordinate mapping is a method of documenting salient features of hyolaryngeal biomechanics in the pharyngeal phase of swallowing. This methodology uses image analysis software to record coordinates of anatomical landmarks. These coordinates are imported into an excel macro and translated into kinematic variables of interest useful in dysphagia research.

Medicine

Ultrasound Assessment of Endothelial Function: A Technical Guideline of the Flow-mediated Dilation Test

Paula Rodriguez-Miguelez¹, Nichole Seigler¹, Ryan A. Harris^1,2

¹Division of Clinical and Translational Sciences, Georgia Prevention Institute, Georgia Regents University, ²Sport and Exercise Science Research Institute, University of Ulster

The flow mediated dilation (FMD) test is the most commonly utilized, non-invasive, ultrasound assessment of endothelial function in humans. Although the FMD test has been related with the prediction of future cardiovascular disease and events, it is a physiological assessment with many inherent confounding factors that need to be considered.