Musashino University

1 ARTICLES PUBLISHED IN JoVE

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Neuroscience

Intracerebroventricular Treatment with Resiniferatoxin and Pain Tests in Mice
Akihiro Fukushima 1,2, Moeko Fujii 1, Hideki Ono 1,2
1Laboratory of Clinical Pharmacy and Pharmacology, Musashino University, 2Research Institute of Pharmaceutical Sciences, Musashino University

The transient receptor potential vanilloid type 1 (TRPV1) in the supraspinal region has been suggested to play some roles in the brain function. Described here is a protocol for intracerebroventricular injection of resiniferatoxin for supraspinal TRPV1 desensitization in mice. Procedures for some pain tests are also presented.

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