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South Infirmary Victoria University Hospital

2 ARTICLES PUBLISHED IN JoVE

Medicine

Murine Bioluminescent Hepatic Tumour Model

Simon Rajendran¹, Slawomir Salwa¹, Xuefeng Gao², Sabin Tabirca², Deirdre O'Hanlon³, Gerald C. O'Sullivan¹, Mark Tangney¹

¹Cork Cancer Research Centre, Mercy University Hospital and Leslie C. Quick Jnr. Laboratory, University College Cork, ²Department of Computer Science, University College Cork, ³South Infirmary Victoria University Hospital

This article describes a procedure for the induction of orthotopic bioluminescent liver tumours in mice, and subsequent analysis of tumour growth confined to the liver using live whole body luminescence imaging.

Medicine

Ex Vivo Culture of Patient Tissue & Examination of Gene Delivery

Simon Rajendran¹, Slawomir Salwa¹, Xuefeng Gao², Sabin Tabirca², Deirdre O'Hanlon², Gerald C. O'Sullivan¹, Mark Tangney¹

¹Cork Cancer Research Centre, Mercy University Hospital and Leslie C. Quick Jnr. Laboratory, University College Cork, ²Department of Computer Science, University College Cork

This article describes the culture of patient tissue slices for gene delivery studies and subsequent analysis of gene expression using IVIS bioluminescence imaging.