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Incheon National University

2 ARTICLES PUBLISHED IN JoVE

Neuroscience

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Hannnah Tetteh^*1, Jihwan Lee^*1, Jinho Lee², Jae Geun Kim³, Sunggu Yang²

¹Department of Biomedical Sciences, City University of Hong Kong, ²Department of Nano-Bioengineering, Incheon National University, ³Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University

We used recording and stimulation electrodes in longitudinal hippocampal brain slices and longitudinally positioned recording and stimulation electrodes in the dorsal hippocampus in vivo to evoke extracellular postsynaptic potentials and demonstrate long-term synaptic plasticity along the longitudinal interlamellar CA1.

Neuroscience

Brain Mapping Using a Graphene Electrode Array

Donggue Kim^*1, Mingyeong Jeong^*1, Elishia Kim¹, Gaeun Kim¹, Junewoo Na¹, Sunggu Yang¹

¹Department of Nano-Bioengineering, Incheon National University

We present a graphene array-based brain mapping procedure to reduce the invasiveness and improve spatiotemporal resolution. Graphene array-based surface electrodes exhibit long-term biocompatibility, mechanical flexibility, and suitability for brain mapping in a convoluted brain. This protocol allows for constructing multiple forms of sensory maps simultaneously and sequentially.