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Medicine

Palatable Western-style Cafeteria Diet as a Reliable Method for Modeling Diet-induced Obesity in Rodents
Sarah-Jane Leigh *1, Michael D. Kendig *1, Margaret J. Morris 1
1Department of Pharmacology, School of Medical Sciences, UNSW Sydney

This protocol describes the use of a highly palatable, western-style cafeteria diet to model overeating and obesity in rodents. Here, we provide a detailed outline of food selection, preparation and measurement, and explain methodological factors that assist in generating a robust and reproducible phenotype.

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