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National University Hospital

2 ARTICLES PUBLISHED IN JoVE

Cancer Research

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System

Sin Mun Tham¹, Kesavan Esuvaranathan^1,2, Ratha Mahendran¹

¹Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, ²Department of Urology, National University Hospital

This protocol describes the generation of murine orthotopic bladder tumors in female C57BL/6J mice and the monitoring of tumor growth.

Medicine

Measuring Retinal Vessel Diameter from Mouse Fluorescent Angiography Images

Andrea García-Llorca¹, Hallur Reynisson¹, Thor Eysteinsson^1,2

¹Department of Physiology, Biomedical Center, Faculty of Medicine, University of Iceland, ²Department of Ophthalmology, National University Hospital

Mouse retinal vasculature is particularly interesting in understanding the mechanisms of vascular pattern formation. This protocol automatically measures the diameter of mouse retinal vessels from fluorescent angiography fundus images at a fixed distance from the optic disk.