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Robert Bosch Hospital

2 ARTICLES PUBLISHED IN JoVE

Medicine

Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders

Peter Ong¹, Anastasios Athanasiadis¹, Udo Sechtem¹

¹Department of Cardiology, Robert-Bosch-Krankenhaus

Intracoronary acetylcholine testing has been established for the assessment of epicardial coronary spasm more than 30 years ago. Recently, the focus has shifted towards the microcirculation and it has been shown that microvascular spasm can be detected using ACH-testing. This article describes the ACH-test and its implementation in daily routine.

Medicine

Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders

Andreas Seitz¹, Sascha Beck¹, Valeria Martínez Pereyra¹, Raffi Bekeredjian¹, Udo Sechtem¹, Peter Ong¹

¹Department of Cardiology and Angiology, Robert Bosch Hospital

Coronary vasomotion disorders represent frequent functional causes of angina in patients with unobstructed coronaries. The underlying mechanism of angina (endotype) in these patients can be determined by a comprehensive invasive diagnostic procedure based on acetylcholine provocation testing followed by Doppler-derived assessment of the coronary flow reserve and microvascular resistance.