Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace PigsGábor B Brenner *1,2, Zoltán Giricz *1,2, Rita Garamvölgyi 3,4, András Makkos 1, Zsófia Onódi 1, Nabil V Sayour 1, Tamás G Gergely 1, Tamás Baranyai 1, Örs Petneházy 3,4, Dénes Kőrösi 3, Gergő P. Szabó 3, Hajnalka Vago 5, Zsófia Dohy 5, Csilla Czimbalmos 5, Béla Merkely 5, Swetlana Boldin-Adamsky 6, Elena Feinstein 6, Iván G Horváth 7, Péter Ferdinandy 1,2
1Department of Pharmacology and Pharmacotherapy, Semmelweis University, 2Pharmahungary Group, 3Diagnostic, Radiation Oncology, Research and Teaching Center, Moritz Kaposi Somogy County Teaching Hospital, 4Faculty of Agricultural and Environmental Sciences, Kaposvar University, 5Heart and Vascular Center, Semmelweis University, 6Quark Pharmaceuticals, Inc, 7Heart Institute, Medical School, University of Pécs
The overall goal of the current study is to present the techniques of induction of myocardial infarction (MI) and post-myocardial infarction heart failure (post-MI HF) in closed-chest, adult Göttingen minipigs and the characterization of post-MI HF model in Göttingen minipigs as compared to Landrace pigs.
