Tibial Nerve Transection - A Standardized Model for Denervation-induced Skeletal Muscle Atrophy in MiceJane A. E. Batt 1, James Ralph Bain 2
1Keenan Research Centre of the LiKaShing Knowledge Institute, St Michaels Hospital, 2Department of Surgery, McMaster University
The tibial nerve transection model is a well-tolerated, validated, and reproducible model of skeletal muscle atrophy. The model surgical protocol is described and demonstrated in C57Black6 mice.
