Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural ProductsRenata Sigrist 1, Bruno S. Paulo 1, Célio F. F. Angolini 2, Luciana G. De Oliveira 1
1Department of Organic Chemistry, Institute of Chemistry, University of Campinas (UNICAMP), 2Center for Natural and Human Sciences, Federal University of ABC (UFABC)
A mass spectrometry-guided genome mining protocol is established and described here. It is based on genome sequence information and LC-MS/MS analysis and aims to facilitate identification of molecules from complex microbial and plant extracts.
