Tianjin Research Institute for Water Transport Engineering, M.O.T.

1 ARTICLES PUBLISHED IN JoVE

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Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size (LEfSe) in Microbiome Data

Fang Chang^*1, Shishi He^*2, Chenyuan Dang³

¹Marine Resources Research Centre, Tianjin Research Institute for Water Transport Engineering, M.O.T., ²Key Laboratory of Regional Energy Systems Optimization, Ministry of Education, College of Environmental Science and Engineering, North China Electric Power University, ³School of Environmental Science and Engineering, Huazhong University of Science and Technology

LEfSe (LDA Effect Size) is a tool for high-dimensional biomarker mining to identify genomic features (such as genes, pathways, and taxonomies) that significantly characterize two or more groups in microbiome data.