第 40 章
階層的な幹細胞システム: 血球の形成
血管系の概要
The vascular system comprises an extensive network of arteries, capillaries, and veins. The vascular system can be broadly divided into the blood and ...
血管新生のメカニズム
Blood vessel formation starts early during embryonic development, around day 7. In the extraembryonic yolk sac, mesodermal precursor cells called ...
血管新生と血液供給の調節
Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or ...
造血
The process of blood cell formation is called hematopoiesis. Hematopoiesis starts early during development, on the seventh day of embryogenesis. This ...
造血幹細胞の多能性
The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in ...
リネージュコミットメント
Commitment is the process whereby stem cells:
lose their ability to form all cell types and
irreversibly change into a specific type.
The ...
赤血球生成
Red blood cells (RBCs) transport oxygen to all body tissues. These cells survive only for 120 days and then need to be replenished. Erythropoiesis ...
共通骨髄系前駆細胞の分化
Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are ...
造血幹細胞の制御
All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a ...
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