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Isothermal Titration Calorimetry for Evaluating PROTACS-Induced Ternary Complex Formation

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179 Views

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01:16 min

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January 12th, 2024

DOI :

10.3791/200654-v

January 12th, 2024

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Wei Jiang¹, Holly Soutter¹

¹Center for the Development of Therapeutics, The Broad Institute of MIT and Harvard

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Keywords Isothermal Titration Calorimetry

Ternary Complex Formation

Micro Calorimeter

Positive Cooperativity

シリーズから

Characterization of Ternary Complex Formation in PROTACs Using Biophysical Assays

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