Division of Infectious Diseases,
Department of Medicine and Vancouver Costal Health Research Institute,
Division of Infectious Diseases, Department of Medicine and Vancouver Costal Health Research Institute
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1alpha,25-dihydroxyvitamin D(3)-induced myeloid cell differentiation is regulated by a vitamin D receptor-phosphatidylinositol 3-kinase signaling complex.
The Journal of experimental medicine Dec, 1999 | Pubmed ID: 10587349
Kinome analysis of host response to mycobacterial infection: a novel technique in proteomics.
Infection and immunity Oct, 2003 | Pubmed ID: 14500469
Stable gene silencing in human monocytic cell lines using lentiviral-delivered small interference RNA. Silencing of the p110alpha isoform of phosphoinositide 3-kinase reveals differential regulation of adherence induced by 1alpha,25-dihydroxycholecalciferol and bacterial lipopolysaccharide.
The Journal of biological chemistry Mar, 2004 | Pubmed ID: 14672955
Dual receptors and distinct pathways mediate interleukin-1 receptor-associated kinase degradation in response to lipopolysaccharide. Involvement of CD14/TLR4, CR3, and phosphatidylinositol 3-kinase.
The Journal of biological chemistry Jun, 2004 | Pubmed ID: 15069085
Quantitative analysis of phagolysosome fusion in intact cells: inhibition by mycobacterial lipoarabinomannan and rescue by an 1alpha,25-dihydroxyvitamin D3-phosphoinositide 3-kinase pathway.
Journal of cell science Apr, 2004 | Pubmed ID: 15090599
Mycobacterium bovis BCG urease attenuates major histocompatibility complex class II trafficking to the macrophage cell surface.
Infection and immunity Jul, 2004 | Pubmed ID: 15213164
Cross-talk between CD14 and complement receptor 3 promotes phagocytosis of mycobacteria: regulation by phosphatidylinositol 3-kinase and cytohesin-1.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2005 | Pubmed ID: 15778383
Mycobacterial manipulation of the host cell.
FEMS microbiology reviews Nov, 2005 | Pubmed ID: 16040149
Mycobacterium bovis BCG attenuates surface expression of mature class II molecules through IL-10-dependent inhibition of cathepsin S.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2005 | Pubmed ID: 16210638
Mycobacterium avium subsp. paratuberculosis PtpA is an endogenous tyrosine phosphatase secreted during infection.
Infection and immunity Dec, 2006 | Pubmed ID: 16982836
Lipoamide dehydrogenase mediates retention of coronin-1 on BCG vacuoles, leading to arrest in phagosome maturation.
Journal of cell science Aug, 2007 | Pubmed ID: 17652161
Mycobacterium bovis bacillus Calmette-Guérin secreting active cathepsin S stimulates expression of mature MHC class II molecules and antigen presentation in human macrophages.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2007 | Pubmed ID: 17911599
Mycobacterium bovis BCG disrupts the interaction of Rab7 with RILP contributing to inhibition of phagosome maturation.
Journal of leukocyte biology Dec, 2007 | Pubmed ID: 18040083
Mycobacterium tuberculosis virulence is mediated by PtpA dephosphorylation of human vacuolar protein sorting 33B.
Cell host & microbe May, 2008 | Pubmed ID: 18474358
Detection of activated Rab7 GTPase with an immobilized RILP probe.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19347311
A broad-range of recombination cloning vectors in mycobacteria.
Plasmid Nov, 2009 | Pubmed ID: 19647016
Protein kinase and phosphatase signaling in Mycobacterium tuberculosis physiology and pathogenesis.
Biochimica et biophysica acta Mar, 2010 | Pubmed ID: 19766738
Mycobacterial nucleoside diphosphate kinase blocks phagosome maturation in murine RAW 264.7 macrophages.
PloS one Jan, 2010 | Pubmed ID: 20098737
Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2011 | Pubmed ID: 22087003
Mycobacterium tuberculosis nucleoside diphosphate kinase inactivates small GTPases leading to evasion of innate immunity.
PLoS pathogens , 2013 | Pubmed ID: 23874203
Immunoevasion and immunosuppression of the macrophage by Mycobacterium tuberculosis.
Immunological reviews Mar, 2015 | Pubmed ID: 25703562
Improving the Immunogenicity of the Mycobacterium bovis BCG Vaccine by Non-Genetic Bacterial Surface Decoration Using the Avidin-Biotin System.
PloS one , 2015 | Pubmed ID: 26716832
Mycobacterium tuberculosis Cpn60.2 (GroEL2) blocks macrophage apoptosis via interaction with mitochondrial mortalin.
Biology open Apr, 2017 | Pubmed ID: 28288970
Expression of Cathepsin S in BCG converts it into a pro-apoptotic and highly immunogenic strain.
Vaccine Apr, 2017 | Pubmed ID: 28318770
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