Cardiovascular and Metabolic Sciences,
Lerner Research Institute; Women’s Health Institute,
Gynecologic Oncology,
Women’s Health Institute and Department of Molecular Medicine,
Cleveland Clinic Lerner College of Medicine,
Cardiovascular and Metabolic Sciences, Lerner Research Institute; Women’s Health Institute,
Gynecologic Oncology, Women’s Health Institute and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine
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The role of syndecans in the regulation of body weight and synaptic plasticity.
The international journal of biochemistry & cell biology , 2008 | Pubmed ID: 17698399
Small-molecule melanin-concentrating hormone-1 receptor antagonists require brain penetration for inhibition of food intake and reduction in body weight.
The Journal of pharmacology and experimental therapeutics Jan, 2008 | Pubmed ID: 17932246
Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats.
Diabetes Nov, 2008 | Pubmed ID: 18716045
Diet-induced obese mice are leptin insufficient after weight reduction.
Obesity (Silver Spring, Md.) Sep, 2009 | Pubmed ID: 19373220
Enhanced anorexigenic signaling in lean obesity resistant syndecan-3 null mice.
Neuroscience Dec, 2010 | Pubmed ID: 20923696
Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival.
Endocrine-related cancer Aug, 2011 | Pubmed ID: 21636700
Myosin II isoform switching mediates invasiveness after TGF-β-induced epithelial-mesenchymal transition.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2011 | Pubmed ID: 22025714
Leptin regulates cyclin D1 in luminal epithelial cells of mouse MMTV-Wnt-1 mammary tumors.
Journal of cancer research and clinical oncology Sep, 2012 | Pubmed ID: 22692856
Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells.
Endocrine-related cancer Dec, 2013 | Pubmed ID: 24025407
Inflammation-induced functional connectivity of melanin-concentrating hormone and IL-10.
Peptides May, 2014 | Pubmed ID: 24556508
Development of a Fluorescent Reporter System to Delineate Cancer Stem Cells in Triple-Negative Breast Cancer.
Stem cells (Dayton, Ohio) Jul, 2015 | Pubmed ID: 25827713
Cisplatin induces stemness in ovarian cancer.
Oncotarget May, 2016 | Pubmed ID: 27105520
Reporter Systems to Study Cancer Stem Cells.
Methods in molecular biology (Clifton, N.J.) , 2016 | Pubmed ID: 27221339
Induction of HEXIM1 activities by HMBA derivative 4a1: Functional consequences and mechanism.
Cancer letters 08, 2016 | Pubmed ID: 27238569
Increased cancer stem cell invasion is mediated by myosin IIB and nuclear translocation.
Oncotarget Jul, 2016 | Pubmed ID: 27285763
Healthcare Commercialization Programs: Improving the Efficiency of Translating Healthcare Innovations From Academia Into Practice.
IEEE journal of translational engineering in health and medicine , 2016 | Pubmed ID: 27766188
Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression.
Cell stem cell 04, 2017 | Pubmed ID: 28089910
RBP4-STRA6 Pathway Drives Cancer Stem Cell Maintenance and Mediates High-Fat Diet-Induced Colon Carcinogenesis.
Stem cell reports 08, 2017 | Pubmed ID: 28689994
STAT3 activation by leptin receptor is essential for TNBC stem cell maintenance.
Endocrine-related cancer 08, 2017 | Pubmed ID: 28729467
NIH Centers for Accelerated Innovations Program: principles, practices, successes and challenges.
Nature reviews. Drug discovery 10, 2017 | Pubmed ID: 28775338
CD55 regulates self-renewal and cisplatin resistance in endometrioid tumors.
The Journal of experimental medicine Sep, 2017 | Pubmed ID: 28838952
Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase.
Nature communications 02, 2018 | Pubmed ID: 29422613
Leptin Regulation of Cancer Stem Cells in Breast and Gynecologic Cancer.
Endocrinology 08, 2018 | Pubmed ID: 29955847
Five-Part Pentameric Nanocomplex Shows Improved Efficacy of Doxorubicin in CD44+ Cancer Cells.
ACS omega Nov, 2017 | Pubmed ID: 30023561
Targeting Cancer Stemness in the Clinic: From Hype to Hope.
Cell stem cell 01, 2019 | Pubmed ID: 30595497
Cancer Connectors: Connexins, Gap Junctions, and Communication.
Frontiers in oncology , 2018 | Pubmed ID: 30622930
Therapeutic strategies to induce ERα in luminal breast cancer to enhance tamoxifen efficacy.
Endocrine-related cancer 08, 2019 | Pubmed ID: 31167163
A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling.
Cell chemical biology 08, 2019 | Pubmed ID: 31178408
Thy-1 predicts poor prognosis and is associated with self-renewal in ovarian cancer.
Journal of ovarian research Nov, 2019 | Pubmed ID: 31735168
Phosphorylation of the histone demethylase KDM5B and regulation of the phenotype of triple negative breast cancer.
Scientific reports 11, 2019 | Pubmed ID: 31776402
Nudix Hydrolase NUDT16 Regulates 53BP1 Protein by Reversing 53BP1 ADP-Ribosylation.
Cancer research 03, 2020 | Pubmed ID: 31911551
Use of Transabdominal Ultrasound for the detection of intra-peritoneal tumor engraftment and growth in mouse xenografts of epithelial ovarian cancer.
PloS one , 2020 | Pubmed ID: 32348309
Signaling within the epithelial ovarian cancer tumor microenvironment: the challenge of tumor heterogeneity.
Annals of translational medicine Jul, 2020 | Pubmed ID: 32793749
Impact of antibiotic treatment during platinum chemotherapy on survival and recurrence in women with advanced epithelial ovarian cancer.
Gynecologic oncology Sep, 2020 | Pubmed ID: 32950250
CK2 kinase-mediated PHF8 phosphorylation controls TopBP1 stability to regulate DNA replication.
Nucleic acids research 11, 2020 | Pubmed ID: 33010150
Elliott G. Richards*,1,
Jenna M. Rehmer*,2,
Melissa A. Mathes3,
Emily L. Esakov1,
Chad Braley1,
Amy Joehlin-Price4,
Andres Chiesa-Vottero4,
Ofer Reizes1,5
1Cardiovascular and Metabolic Sciences, Lerner Research Institute; Women’s Health Institute, Cleveland Clinic,
2Women’s Health Institute, Cleveland Clinic,
3Department of Obstetrics and Gynecology, 983255 Nebraska Medical Center, University of Nebraska Medical Center,
4Anatomic Pathology, Cleveland Clinic,
5Gynecologic Oncology, Women’s Health Institute and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic
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