Alexander Hergovich has not added Biography.
If you are Alexander Hergovich and would like to personalize this page please email our Author Liaison for assistance.
Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL.
Nature cell biology Jan, 2003 | Pubmed ID: 12510195
Relevance of nuclear and cytoplasmic von hippel lindau protein expression for renal carcinoma progression.
The American journal of pathology Sep, 2003 | Pubmed ID: 12937142
Regulation of NDR2 protein kinase by multi-site phosphorylation and the S100B calcium-binding protein.
The Journal of biological chemistry May, 2004 | Pubmed ID: 15037617
Human NDR kinases are rapidly activated by MOB proteins through recruitment to the plasma membrane and phosphorylation.
Molecular and cellular biology Sep, 2005 | Pubmed ID: 16135814
Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3.
Molecular and cellular biology Dec, 2005 | Pubmed ID: 16314523
NDR kinases regulate essential cell processes from yeast to humans.
Nature reviews. Molecular cell biology Apr, 2006 | Pubmed ID: 16607288
The human tumour suppressor LATS1 is activated by human MOB1 at the membrane.
Biochemical and biophysical research communications Jun, 2006 | Pubmed ID: 16674920
Priming-dependent phosphorylation and regulation of the tumor suppressor pVHL by glycogen synthase kinase 3.
Molecular and cellular biology Aug, 2006 | Pubmed ID: 16847331
Centrosome-associated NDR kinase regulates centrosome duplication.
Molecular cell Feb, 2007 | Pubmed ID: 17317633
Mammalian NDR protein kinases: from regulation to a role in centrosome duplication.
Biochimica et biophysica acta Jan, 2008 | Pubmed ID: 17881309
Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors.
Cellular signalling Aug, 2008 | Pubmed ID: 18555663
NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis.
Current biology : CB Dec, 2008 | Pubmed ID: 19062280
Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin.
Molecular biology of the cell Feb, 2009 | Pubmed ID: 19073886
Mammalian NDR/LATS protein kinases in hippo tumor suppressor signaling.
BioFactors (Oxford, England) Jul-Aug, 2009 | Pubmed ID: 19484742
VHL loss causes spindle misorientation and chromosome instability.
Nature cell biology Aug, 2009 | Pubmed ID: 19620968
The MST1 and hMOB1 tumor suppressors control human centrosome duplication by regulating NDR kinase phosphorylation.
Current biology : CB Nov, 2009 | Pubmed ID: 19836237
TAZ-mediated crosstalk between Wnt and Hippo signaling.
Developmental cell Apr, 2010 | Pubmed ID: 20412766
Ablation of the kinase NDR1 predisposes mice to the development of T cell lymphoma.
Science signaling , 2010 | Pubmed ID: 20551432
Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases.
Molecular and cellular biology Sep, 2010 | Pubmed ID: 20624913
Human NDR kinases control G(1)/S cell cycle transition by directly regulating p21 stability.
Molecular and cellular biology Apr, 2011 | Pubmed ID: 21262772
MOB control: reviewing a conserved family of kinase regulators.
Cellular signalling Sep, 2011 | Pubmed ID: 21539912
Downstream of human NDR kinases: impacting on c-myc and p21 protein stability to control cell cycle progression.
Cell cycle (Georgetown, Tex.) Jun, 2011 | Pubmed ID: 21593588
MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis.
Molecular and cellular biology Sep, 2011 | Pubmed ID: 21730291
Mammalian Hippo signalling: a kinase network regulated by protein-protein interactions.
Biochemical Society transactions Feb, 2012 | Pubmed ID: 22260677
Hippo signalling in the G2/M cell cycle phase: lessons learned from the yeast MEN and SIN pathways.
Seminars in cell & developmental biology Sep, 2012 | Pubmed ID: 22525225
YAP-Hippo signalling downstream of leukemia inhibitory factor receptor: implications for breast cancer.
Breast cancer research : BCR Dec, 2012 | Pubmed ID: 23216692
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved