Anthony J. Hannan

Environmental enrichment slows disease progression in R6/2 Huntington's disease mice.

International Brain Research Organization--Sixth World Congress of Neuroscience. 10-15 July 2003, Prague, Czech Republic.

Genetic and environmental factors in the pathogenesis of Huntington's disease.

Society for neuroscience-33rd annual meeting.

Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism.

Australian Neuroscience Society--24th annual meeting. 27-30 January 2004, Melbourne, Australia.

Huntington's disease: which drugs might help patients?

Decreased hippocampal cell proliferation in R6/1 Huntington's mice.

Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice.

Molecular mediators, environmental modulators and experience-dependent synaptic dysfunction in Huntington's disease.

Impaired learning-dependent cortical plasticity in Huntington's disease transgenic mice.

Activity-dependent regulation of synapse and dendritic spine morphology in developing barrel cortex requires phospholipase C-beta1 signalling.

Australian Neuroscience Society--25th Annual Meeting. 30 January-2 February 2005, Perth, Australia.

Deficits in experience-dependent cortical plasticity and sensory-discrimination learning in presymptomatic Huntington's disease mice.

Nature, nurture and neurology: gene-environment interactions in neurodegenerative disease. FEBS Anniversary Prize Lecture delivered on 27 June 2004 at the 29th FEBS Congress in Warsaw.

Novel therapeutic targets for Huntington's disease.

Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine.

Gene-environment interactions, neuronal dysfunction and pathological plasticity in Huntington's disease.

Neurogenesis in the R6/1 transgenic mouse model of Huntington's disease: effects of environmental enrichment.

Enriched environments, experience-dependent plasticity and disorders of the nervous system.

European neuroscience - Federation of European Neuroscience Societies 5th Forum. 8-12 July 2006, Vienna, Austria.

Molecular mechanisms mediating pathological plasticity in Huntington's disease and Alzheimer's disease.

Olfactory abnormalities in Huntington's disease: decreased plasticity in the primary olfactory cortex of R6/1 transgenic mice and reduced olfactory discrimination in patients.

Regulators of adult neurogenesis in the healthy and diseased brain.

Dynamic mutations as digital genetic modulators of brain development, function and dysfunction.

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.

Enviromimetics: exploring gene environment interactions to identify therapeutic targets for brain disorders.

International Brain Research Organization--Seventh World Congress of Neuroscience. 12-17 July 2007, Melbourne, Victoria, Australia.

Gene-environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington's disease transgenic mice.

Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease.

Magnetic resonance imaging as an approach towards identifying neuropathological biomarkers for Huntington's disease.

PLC-beta1 knockout mice as a model of disrupted cortical development and plasticity: behavioral endophenotypes and dysregulation of RGS4 gene expression.

Simple sequence repeats: genetic modulators of brain function and behavior.

Environmental enrichment ameliorates a motor coordination deficit in a mouse model of Rett syndrome--Mecp2 gene dosage effects and BDNF expression.

Effects of enriched environment on animal models of neurodegenerative diseases and psychiatric disorders.

Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-D-aspartic acid receptor up-regulation.

Regulator of G-protein signalling 4 expression is not altered in the prefrontal cortex in schizophrenia.

Role of muscarinic receptors in the activity of N-desmethylclozapine: reversal of hyperactivity in the phospholipase C knockout mouse.

Sex-specific behavioural effects of environmental enrichment in a transgenic mouse model of amyotrophic lateral sclerosis.

European Neuroscience - Sixth Biennial FENS Forum.

Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease.

Sensitivity to MK-801 in phospholipase C-β1 knockout mice reveals a specific NMDA receptor deficit.

Towards a therapy for Huntington's disease (Commentary on Giampà et al.).

Modeling brain reserve: experience-dependent neuronal plasticity in healthy and Huntington's disease transgenic mice.

The neurobiology of brain and cognitive reserve: mental and physical activity as modulators of brain disorders.

Tandem repeat polymorphisms: modulators of disease susceptibility and candidates for 'missing heritability'.

Australian Neuroscience Society - 30th Annual Meeting and Australian Physiological Society - 50th Anniversary Meeting.

Environmental enrichment reduces neuronal intranuclear inclusion load but has no effect on messenger RNA expression in a mouse model of Huntington disease.

European Neuroscience--Seventh Biennial FENS Forum.

Environmental enrichment: a cure for cancer? It's all in the mind.

TRPing up the genome: Tandem repeat polymorphisms as dynamic sources of genetic variability in health and disease.

Increased adult hippocampal neurogenesis and abnormal migration of adult-born granule neurons is associated with hippocampal-specific cognitive deficits in phospholipase C-β1 knockout mice.

Phospholipase C beta 1 expression in the dorsolateral prefrontal cortex from patients with schizophrenia at different stages of illness.

Mechanisms mediating brain and cognitive reserve: experience-dependent neuroprotection and functional compensation in animal models of neurodegenerative diseases.

Gene-environment interactions and construct validity in preclinical models of psychiatric disorders.

The latent stem cell population is retained in the hippocampus of transgenic Huntington's disease mice but not wild-type mice.

Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise.

Sexually dimorphic serotonergic dysfunction in a mouse model of Huntington's disease and depression.

Retinal dysfunction, photoreceptor protein dysregulation and neuronal remodelling in the R6/1 mouse model of Huntington's disease.

Mutation of Gtf2ird1 from the Williams-Beuren syndrome critical region results in facial dysplasia, motor dysfunction, and altered vocalisations.

Behavioural state differentially engages septohippocampal cholinergic and GABAergic neurons in R6/1 Huntington's disease mice.

Effect of enhanced voluntary physical exercise on brain levels of monoamines in Huntington disease mice.

Long-term behavioral and NMDA receptor effects of young-adult corticosterone treatment in BDNF heterozygous mice.

Effects of environmental manipulations in genetically targeted animal models of affective disorders.

Exploring the efficacy of constraint in animal models of stroke: meta-analysis and systematic review of the current evidence.

Enhancement of cognitive function in models of brain disease through environmental enrichment and physical activity.

Hippocampal neurogenesis, cognitive deficits and affective disorder in Huntington's disease.

Neurocardiac dysregulation and neurogenic arrhythmias in a transgenic mouse model of Huntington's disease.

Differential effects of early environmental enrichment on emotionality related behaviours in Huntington's disease transgenic mice.

The relationship between cortisol and verbal memory in the early stages of Huntington's disease.

Nature, nurture and neurobiology: Gene-environment interactions in neuropsychiatric disorders.

Impaired basal and running-induced hippocampal neurogenesis coincides with reduced Akt signaling in adult R6/1 HD mice.

Depression-related behaviours displayed by female C57BL/6J mice during abstinence from chronic ethanol consumption are rescued by wheel-running.

Tandem repeat polymorphisms. Preface.

Tandem repeat polymorphisms: Mediators of genetic plasticity, modulators of biological diversity and dynamic sources of disease susceptibility.

Towards environmental construct validity in animal models of CNS disorders: optimizing translation of preclinical studies.

Characterizing social behavior in genetically targeted mouse models of brain disorders.

A Tale of Two Maladies? Pathogenesis of Depression with and without the Huntington's Disease Gene Mutation.

Translating preclinical environmental enrichment studies for the treatment of autism and other brain disorders: comment on Woo and Leon (2013).

Positive environmental modification of depressive phenotype and abnormal hypothalamic-pituitary-adrenal axis activity in female C57BL/6J mice during abstinence from chronic ethanol consumption.

Short-term memory acquisition in female Huntington's disease mice is vulnerable to acute stress.

Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait.

Epigenetic modifications in trinucleotide repeat diseases.

Cortisol and depression in pre-diagnosed and early stage Huntington's disease.

Decanalization mediating gene-environment interactions in schizophrenia and other psychiatric disorders with neurodevelopmental etiology.

Beyond loss of frataxin: the complex molecular pathology of Friedreich ataxia.

Noninvasive strategies to optimise brain plasticity: from basic research to clinical perspectives.

Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain.

Vascular endothelial growth factor and brain-derived neurotrophic factor in quetiapine treated first-episode psychosis.

Novel ethological endophenotypes in a transgenic mouse model of Huntington's disease.

Sex-specific disruptions in spatial memory and anhedonia in a "two hit" rat model correspond with alterations in hippocampal brain-derived neurotrophic factor expression and signaling.

High stress hormone levels accelerate the onset of memory deficits in male Huntington's disease mice.

Identifying novel interventional strategies for psychiatric disorders: integrating genomics, 'enviromics' and gene-environment interactions in valid preclinical models.

Antidepressant-Like Effect of the Norepinephrine-Dopamine Reuptake Inhibitor Bupropion in a Mouse Model of Huntington's Disease with Dopaminergic Dysfunction.

Effects of chronic stress on the onset and progression of Huntington's disease in transgenic mice.

Ethological endophenotypes are altered by elevated stress hormone levels in both Huntington's disease and wildtype mice.

Long-term effects of combined neonatal and adolescent stress on brain-derived neurotrophic factor and dopamine receptor expression in the rat forebrain.

'Super-Enrichment' Reveals Dose-Dependent Therapeutic Effects of Environmental Stimulation in a Transgenic Mouse Model of Huntington's Disease.

Sexually dimorphic dopaminergic dysfunction in a transgenic mouse model of Huntington's disease.

Reduced susceptibility to induced seizures in the Neuroligin-3(R451C) mouse model of Autism.