Department of Microbiology,
Immunology,
& Cell Biology,
Department of Microbiology, Immunology, & Cell Biology
Cory Robinson is an Associate Professor in the Department of Microbiology, Immunology, & Cell Biology at West Virginia University School of Medicine. He received his Bachelor’s degree from Bowling Green State University, and a Ph.D. from the Miami University.
Dr. Robinson’s research has always been at the interface of host and pathogen interactions. In his first postdoctoral fellowship with Alison O’Brien at the Uniformed Service University, he studied the influence of Shiga toxin on colonization of the mouse intestine and human epithelial cells by Enterohemorrhagic E. coli. He then pursued additional postdoctoral work with Gerard Nau at the University of Pittsburgh School of medicine studying the influence of interleukin (IL)-27 on human macrophage control of Mycobacterium tuberculosis.
Dr. Robinson received a K99 Pathway to Independence Award from the NIH in 2009 that allowed him to establish an independent laboratory that he has continued to fund through the present with NIH and other extramural mechanisms. His research program focuses on the involvement of IL-27 in host immune responses to bacterial infections and vaccination during the neonatal period. This involves neonatal mouse models of infection and vaccination, along with complementary in vitro studies with primary immune cells isolated from neonatal blood.
Murine myeloid-derived suppressor cells are a source of elevated levels of interleukin-27 in early life and compromise control of bacterial infection.
Immunology and cell biology 05, 2019 | Pubmed ID: 30575117
Elevated Levels of Interleukin-27 in Early Life Compromise Protective Immunity in a Mouse Model of Gram-Negative Neonatal Sepsis.
Infection and immunity 02, 2020 | Pubmed ID: 31818960
IL-27 regulation of innate immunity and control of microbial growth.
Future science OA Jun, 2020 | Pubmed ID: 32802395
Neonatal low-density granulocytes internalize and kill bacteria but suppress monocyte function using extracellular DNA.
Journal of cell science Mar, 2021 | Pubmed ID: 33589502
Myeloid-Derived Suppressor Cells Gain Suppressive Function during Neonatal Bacterial Sepsis.
International journal of molecular sciences Jun, 2021 | Pubmed ID: 34208904
The Enigma of Low-Density Granulocytes in Humans: Complexities in the Characterization and Function of LDGs during Disease.
Pathogens (Basel, Switzerland) Aug, 2021 | Pubmed ID: 34578124
The impact of opioid exposure during pregnancy on the human neonatal immune profile.
Pediatric research Dec, 2022 | Pubmed ID: 35288639
Interleukin-27 impairs BCG antigen clearance and T cell stimulatory potential by neonatal dendritic cells.
Current research in microbial sciences , 2023 | Pubmed ID: 36530844
Interleukin-27-dependent transcriptome signatures during neonatal sepsis.
Frontiers in immunology , 2023 | Pubmed ID: 36891292
IL-27 alters inflammatory cytokine expression and limits protective immunity against in a neonatal BCG vaccination model.
Frontiers in immunology , 2024 | Pubmed ID: 38390338
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