Laboratory of Parasitic Diseases,
National Institute of Allergy and Infectious Diseases,
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases
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Vaccination with DNA encoding the immunodominant LACK parasite antigen confers protective immunity to mice infected with Leishmania major.
The Journal of experimental medicine Oct, 1997 | Pubmed ID: 9314562
Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity.
The Journal of experimental medicine Oct, 1998 | Pubmed ID: 9782133
Development of a natural model of cutaneous leishmaniasis: powerful effects of vector saliva and saliva preexposure on the long-term outcome of Leishmania major infection in the mouse ear dermis.
The Journal of experimental medicine Nov, 1998 | Pubmed ID: 9815271
The role of antigen and IL-12 in sustaining Th1 memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2000 | Pubmed ID: 10890924
Toward a defined anti-Leishmania vaccine targeting vector antigens: characterization of a protective salivary protein.
The Journal of experimental medicine Aug, 2001 | Pubmed ID: 11489952
The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure.
The Journal of experimental medicine Nov, 2001 | Pubmed ID: 11714756
Vaccination with heat-killed leishmania antigen or recombinant leishmanial protein and CpG oligodeoxynucleotides induces long-term memory CD4+ and CD8+ T cell responses and protection against leishmania major infection.
The Journal of experimental medicine Jun, 2002 | Pubmed ID: 12070284
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity.
Nature Dec, 2002 | Pubmed ID: 12466842
Immunological and pathological evaluation of rhesus macaques infected with Leishmania major.
Experimental parasitology Mar-Apr, 2003 | Pubmed ID: 12880593
Coinjection with CpG-containing immunostimulatory oligodeoxynucleotides reduces the pathogenicity of a live vaccine against cutaneous Leishmaniasis but maintains its potency and durability.
Infection and immunity Sep, 2003 | Pubmed ID: 12933855
Nonhealing infection despite Th1 polarization produced by a strain of Leishmania major in C57BL/6 mice.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2005 | Pubmed ID: 15728505
Conditions influencing the efficacy of vaccination with live organisms against Leishmania major infection.
Infection and immunity Aug, 2005 | Pubmed ID: 16040984
Prevention and treatment of cutaneous leishmaniasis in primates by using synthetic type D/A oligodeoxynucleotides expressing CpG motifs.
Infection and immunity Aug, 2005 | Pubmed ID: 16041009
Antigen requirements for efficient priming of CD8+ T cells by Leishmania major-infected dendritic cells.
Infection and immunity Oct, 2005 | Pubmed ID: 16177338
A Leishmania amazonensis ZIP family iron transporter is essential for parasite replication within macrophage phagolysosomes.
The Journal of experimental medicine Oct, 2006 | Pubmed ID: 17000865
Uninfected mosquito bites confer protection against infection with malaria parasites.
Infection and immunity May, 2007 | Pubmed ID: 17339356
Vector transmission of leishmania abrogates vaccine-induced protective immunity.
PLoS pathogens Jun, 2009 | Pubmed ID: 19543375
The impact of vector-mediated neutrophil recruitment on cutaneous leishmaniasis.
Cellular microbiology Sep, 2009 | Pubmed ID: 19545276
Leishmania major survival in selective Phlebotomus papatasi sand fly vector requires a specific SCG-encoded lipophosphoglycan galactosylation pattern.
PLoS pathogens , 2010 | Pubmed ID: 21085609
Infection parameters in the sand fly vector that predict transmission of Leishmania major.
PLoS neglected tropical diseases Aug, 2011 | Pubmed ID: 21886852
Evaluation of recombinant Leishmania polyprotein plus glucopyranosyl lipid A stable emulsion vaccines against sand fly-transmitted Leishmania major in C57BL/6 mice.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2012 | Pubmed ID: 23045616
Tracking antigen-specific CD4+ T cells throughout the course of chronic Leishmania major infection in resistant mice.
European journal of immunology Feb, 2013 | Pubmed ID: 23109292
Site-dependent recruitment of inflammatory cells determines the effective dose of Leishmania major.
Infection and immunity Jul, 2014 | Pubmed ID: 24733090
Vaccines against tropical parasitic diseases: a persisting answer to a persisting problem.
Nature immunology May, 2014 | Pubmed ID: 24747701
Cross-species genetic exchange between visceral and cutaneous strains of Leishmania in the sand fly vector.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2014 | Pubmed ID: 25385616
Chronic parasitic infection maintains high frequencies of short-lived Ly6C+CD4+ effector T cells that are required for protection against re-infection.
PLoS pathogens Dec, 2014 | Pubmed ID: 25473946
Cutaneous Infection with Leishmania major Mediates Heterologous Protection against Visceral Infection with Leishmania infantum.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2015 | Pubmed ID: 26371247
The Nlrp3 inflammasome, IL-1β, and neutrophil recruitment are required for susceptibility to a nonhealing strain of Leishmania major in C57BL/6 mice.
European journal of immunology Apr, 2016 | Pubmed ID: 26689285
The Transcriptome of Developmental Stages in Their Natural Sand Fly Vector.
mBio 04, 2017 | Pubmed ID: 28377524
Divergent roles for Ly6C+CCR2+CX3CR1+ inflammatory monocytes during primary or secondary infection of the skin with the intra-phagosomal pathogen Leishmania major.
PLoS pathogens Jun, 2017 | Pubmed ID: 28666021
Gene Expression in Is Regulated Predominantly by Gene Dosage.
mBio 09, 2017 | Pubmed ID: 28900023
NOX2-Derived Reactive Oxygen Species Control Inflammation during Infection by Mediating Infection-Induced Neutrophil Apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 01, 2018 | Pubmed ID: 29158417
Mannose receptor high, M2 dermal macrophages mediate nonhealing infection in a Th1 immune environment.
The Journal of experimental medicine 01, 2018 | Pubmed ID: 29247046
Inflammasomes and Leishmania: in good times or bad, in sickness or in health.
Current opinion in microbiology 12, 2019 | Pubmed ID: 31229882
CRISPR/Cas9 Mutagenesis in Phlebotomus papatasi: the Immune Deficiency Pathway Impacts Vector Competence for Leishmania major.
mBio 08, 2019 | Pubmed ID: 31455654
M2-like, dermal macrophages are maintained via IL-4/CCL24-mediated cooperative interaction with eosinophils in cutaneous leishmaniasis.
Science immunology 04, 2020 | Pubmed ID: 32276966
The Null Hypothesis of IFN-γ and Monocyte Function in Leishmaniasis.
Cell host & microbe 05, 2020 | Pubmed ID: 32407702
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