Department of Pathology,
Department of Immunology,
Duke Human Vaccine Institute
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Cytokines as adjuvants for the induction of anti-human immunodeficiency virus peptide immunoglobulin G (IgG) and IgA antibodies in serum and mucosal secretions after nasal immunization.
Journal of virology Jan, 2002 | Pubmed ID: 11752142
Increased immunogenicity of HIV envelope subunit complexed with alpha2-macroglobulin when combined with monophosphoryl lipid A and GM-CSF.
Vaccine May, 2002 | Pubmed ID: 12009296
Prolonged CD4+ cell/virus load discordance during treatment with protease inhibitor-based highly active antiretroviral therapy: immune response and viral control.
The Journal of infectious diseases Apr, 2003 | Pubmed ID: 12660916
Mast cell-derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infection.
Nature immunology Dec, 2003 | Pubmed ID: 14595438
Gender differences in human immunodeficiency virus type 1-specific CD8 responses in the reproductive tract and colon following nasal peptide priming and modified vaccinia virus Ankara boosting.
Journal of virology Dec, 2004 | Pubmed ID: 15542668
Nasal peptide vaccination elicits CD8 responses and reduces viral burden after challenge with virulent murine cytomegalovirus.
Microbiology and immunology , 2005 | Pubmed ID: 15722596
Mucosal and systemic adjuvant activity of alphavirus replicon particles.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2006 | Pubmed ID: 16505353
Capric acid and hydroxypropylmethylcellulose increase the immunogenicity of nasally administered peptide vaccines.
AIDS research and human retroviruses Jun, 2006 | Pubmed ID: 16796531
Generation of mucosal anti-human immunodeficiency virus type 1 T-cell responses by recombinant Mycobacterium smegmatis.
Clinical and vaccine immunology : CVI Nov, 2006 | Pubmed ID: 16943347
Oral immunogenicity of the plant proteinase bromelain.
International immunopharmacology Dec, 2006 | Pubmed ID: 17161360
Transdermal therapeutic system of carvedilol: effect of hydrophilic and hydrophobic matrix on in vitro and in vivo characteristics.
AAPS PharmSciTech Jan, 2007 | Pubmed ID: 17408218
In vitro and in vivo characterization of anthrax anti-protective antigen and anti-lethal factor monoclonal antibodies after passive transfer in a mouse lethal toxin challenge model to define correlates of immunity.
Infection and immunity Nov, 2007 | Pubmed ID: 17709410
Mast cell activators: a new class of highly effective vaccine adjuvants.
Nature medicine May, 2008 | Pubmed ID: 18425129
An entirely cell-based system to generate single-chain antibodies against cell surface receptors.
Journal of molecular biology May, 2008 | Pubmed ID: 18455737
Nonmucosal alphavirus vaccination stimulates a mucosal inductive environment in the peripheral draining lymph node.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2008 | Pubmed ID: 18566424
Alphavirus replicon particles acting as adjuvants promote CD8+ T cell responses to co-delivered antigen.
Vaccine Aug, 2008 | Pubmed ID: 18582997
The contribution of type I interferon signaling to immunity induced by alphavirus replicon vaccines.
Vaccine Sep, 2008 | Pubmed ID: 18656518
Identification of recombinant antibodies against multiple distinct toll-like receptors by homolog mining a single immune scFv phage library.
Journal of immunological methods Jan, 2009 | Pubmed ID: 19017532
The mast cell activator compound 48/80 is safe and effective when used as an adjuvant for intradermal immunization with Bacillus anthracis protective antigen.
Vaccine Jun, 2009 | Pubmed ID: 19464533
Mast cell-derived particles deliver peripheral signals to remote lymph nodes.
The Journal of experimental medicine Oct, 2009 | Pubmed ID: 19808250
Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissues.
Cell host & microbe Oct, 2009 | Pubmed ID: 19837373
Development of a bead immunoassay to measure Vi polysaccharide-specific serum IgG after vaccination with the Salmonella enterica serovar Typhi Vi polysaccharide.
Clinical and vaccine immunology : CVI Mar, 2010 | Pubmed ID: 20107010
Adenovirus F protein as a delivery vehicle for botulinum B.
BMC immunology Jul, 2010 | Pubmed ID: 20609248
Effective induction of protective systemic immunity with nasally administered vaccines adjuvanted with IL-1.
Vaccine Oct, 2010 | Pubmed ID: 20723629
Scarcity or absence of humoral immune responses in the plasma and cervicovaginal lavage fluids of heavily HIV-1-exposed but persistently seronegative women.
AIDS research and human retroviruses May, 2011 | Pubmed ID: 21091128
Mucosal targeting of a BoNT/A subunit vaccine adjuvanted with a mast cell activator enhances induction of BoNT/A neutralizing antibodies in rabbits.
PloS one Jan, 2011 | Pubmed ID: 21304600
Cytokines: the future of intranasal vaccine adjuvants.
Clinical & developmental immunology , 2011 | Pubmed ID: 21826181
Stable dry powder formulation for nasal delivery of anthrax vaccine.
Journal of pharmaceutical sciences Jan, 2012 | Pubmed ID: 21905034
Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes.
Nature materials Jan, 2012 | Pubmed ID: 22266469
Maximal adjuvant activity of nasally delivered IL-1α requires adjuvant-responsive CD11c(+) cells and does not correlate with adjuvant-induced in vivo cytokine production.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2012 | Pubmed ID: 22345651
A comparison of non-toxin vaccine adjuvants for their ability to enhance the immunogenicity of nasally-administered anthrax recombinant protective antigen.
Vaccine Mar, 2013 | Pubmed ID: 23352329
Evaluation of vaccine-induced antibody responses: impact of new technologies.
Vaccine Jun, 2013 | Pubmed ID: 23583812
Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk.
Journal of virology Jun, 2013 | Pubmed ID: 23596289
A Mast Cell Degranulation Screening Assay for the Identification of Novel Mast Cell Activating Agents.
MedChemComm Jan, 2013 | Pubmed ID: 23667736
A mastoparan-derived peptide has broad-spectrum antiviral activity against enveloped viruses.
Peptides Oct, 2013 | Pubmed ID: 23891650
Salmonella typhimurium impedes innate immunity with a mast-cell-suppressing protein tyrosine phosphatase, SptP.
Immunity Dec, 2013 | Pubmed ID: 24332031
Which comes first: the antigen or the adjuvant?
The Journal of clinical investigation Jun, 2014 | Pubmed ID: 24837429
Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity.
Scientific reports Jun, 2014 | Pubmed ID: 24894817
Effect of particulate adjuvant on the anthrax protective antigen dose required for effective nasal vaccination.
Vaccine Jul, 2015 | Pubmed ID: 26087299
Serological response following re-vaccination with Salmonella typhi Vi-capsular polysaccharide vaccines in healthy adult travellers.
Vaccine Aug, 2015 | Pubmed ID: 26144902
Immunization with the Haemophilus ducreyi trimeric autotransporter adhesin DsrA with alum, CpG or imiquimod generates a persistent humoral immune response that recognizes the bacterial surface.
Vaccine Feb, 2016 | Pubmed ID: 26812077
Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk.
Journal of virology May, 2016 | Pubmed ID: 26937027
Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity.
Journal of controlled release : official journal of the Controlled Release Society Sep, 2015 | Pubmed ID: 27005208
Modified Vaccinia Ankara Virus Vaccination Provides Long-Term Protection against Nasal Rabbitpox Virus Challenge.
Clinical and vaccine immunology : CVI 07, 2016 | Pubmed ID: 27146001
Assessing the satisfaction and burden within an academic animal care and use program.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 09, 2017 | Pubmed ID: 28515151
Effect of endotoxin and alum adjuvant vaccine on peanut allergy.
The Journal of allergy and clinical immunology 02, 2018 | Pubmed ID: 28927819
Vaccine adjuvants: Softness makes it better.
Nature materials 01, 2018 | Pubmed ID: 29358771
Mast cell activators as novel immune regulators.
Current opinion in pharmacology 08, 2018 | Pubmed ID: 29843056
Perivascular dendritic cells elicit anaphylaxis by relaying allergens to mast cells via microvesicles.
Science (New York, N.Y.) 11, 2018 | Pubmed ID: 30409859
Nasal peanut+ CpG immunotherapy enhances peanut-specific IFN-γ in Th2 cells and IL-10 in non-Th2 cells in mice.
Allergy 11, 2019 | Pubmed ID: 30746720
Identification of Novel Mast Cell Activators Using Cell-Based High-Throughput Screening.
SLAS discovery : advancing life sciences R & D 07, 2019 | Pubmed ID: 30917061
Optimized Mucosal Modified Vaccinia Virus Ankara Prime/Soluble gp120 Boost HIV Vaccination Regimen Induces Antibody Responses Similar to Those of an Intramuscular Regimen.
Journal of virology 07, 2019 | Pubmed ID: 31068425
Softness makes it better.
Nature materials Feb, 2018 | Pubmed ID: 31745266
Novel mucosal adjuvant, mastoparan-7, improves cocaine vaccine efficacy.
NPJ vaccines , 2020 | Pubmed ID: 32047657
Novel mucosal adjuvant, mastoparan-7, improves cocaine vaccine efficacy.
NPJ vaccines Feb, 2020 | Pubmed ID: 33536438
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