Department of Biochemistry and Molecular Biology
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A general chemical shift decomposition method for hyperpolarized (13) C metabolite magnetic resonance imaging.
Magnetic resonance in chemistry : MRC Apr, 2016 | Pubmed ID: 27060361
Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate.
Scientific reports 05, 2016 | Pubmed ID: 27150735
Accelerated chemical shift imaging of hyperpolarized (13) C metabolites.
Magnetic resonance in medicine 10, 2016 | Pubmed ID: 27373705
Using a novel NQO1 bioactivatable drug, beta-lapachone (ARQ761), to enhance chemotherapeutic effects by metabolic modulation in pancreatic cancer.
Journal of surgical oncology Jul, 2017 | Pubmed ID: 28346693
A comprehensive analysis of myocardial substrate preference emphasizes the need for a synchronized fluxomic/metabolomic research design.
American journal of physiology. Heart and circulatory physiology Jun, 2017 | Pubmed ID: 28411229
The NQO1 bioactivatable drug, β-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism.
The Journal of biological chemistry 11, 2017 | Pubmed ID: 28916726
Sensitivity enhancement for detection of hyperpolarized C MRI probes with H spin coupling introduced by enzymatic transformation in vivo.
Magnetic resonance in medicine 07, 2018 | Pubmed ID: 29193287
The effect of Ho doping on C dynamic nuclear polarization at 5 T.
Physical chemistry chemical physics : PCCP Jan, 2018 | Pubmed ID: 29242884
Probing cardiac metabolism by hyperpolarized 13C MR using an exclusively endogenous substrate mixture and photo-induced nonpersistent radicals.
Magnetic resonance in medicine 05, 2018 | Pubmed ID: 29411415
In vivo hyperpolarization transfer in a clinical MRI scanner.
Magnetic resonance in medicine 08, 2018 | Pubmed ID: 29488244
A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity.
The Journal of biological chemistry 06, 2018 | Pubmed ID: 29739849
Cancer in the crosshairs: targeting cancer metabolism with hyperpolarized carbon-13 MRI technology.
NMR in biomedicine 10, 2019 | Pubmed ID: 29870085
Hyperpolarized C MRI: Path to Clinical Translation in Oncology.
Neoplasia (New York, N.Y.) 01, 2019 | Pubmed ID: 30472500
Kinetic Analysis of Hepatic Metabolism Using Hyperpolarized Dihydroxyacetone.
Journal of chemical information and modeling 01, 2019 | Pubmed ID: 30602117
Metabolomic profiles differ among unique genotypes of a threatened Caribbean coral.
Scientific reports 04, 2019 | Pubmed ID: 30988456
Nuclear Magnetic Resonance Measurement of Metabolic Flux Using C and H Signals.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 31127544
Regulation of renal NaDC1 expression and citrate excretion by NBCe1-A.
American journal of physiology. Renal physiology 08, 2019 | Pubmed ID: 31188034
Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation.
Cancer discovery 09, 2019 | Pubmed ID: 31189531
Single-walled carbon nanotubes repress viral-induced defense pathways through oxidative stress.
Nanotoxicology 11, 2019 | Pubmed ID: 31328592
Remodeling of substrate consumption in the murine sTAC model of heart failure.
Journal of molecular and cellular cardiology 09, 2019 | Pubmed ID: 31340162
The influence of Ho doping on C DNP in the presence of BDPA.
Physical chemistry chemical physics : PCCP Aug, 2019 | Pubmed ID: 31414686
Aqueous humor metabolite profile of pseudoexfoliation glaucoma is distinctive.
Molecular omics 10, 2020 | Pubmed ID: 32149291
A noninvasive method to study the evolution of extracellular fluid volume in mice using time-domain nuclear magnetic resonance.
American journal of physiology. Renal physiology 07, 2020 | Pubmed ID: 32475134
HDO production from [H]glucose Quantitatively Identifies Warburg Metabolism.
Scientific reports 06, 2020 | Pubmed ID: 32483190
Branched chain amino acids and carbohydrate restriction exacerbate ketogenesis and hepatic mitochondrial oxidative dysfunction during NAFLD.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Nov, 2020 | Pubmed ID: 32918763
N-carnitine, a novel endogenous hyperpolarized MRI probe with long signal lifetime.
Magnetic resonance in medicine 04, 2021 | Pubmed ID: 33179825
Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease.
Molecular metabolism 03, 2021 | Pubmed ID: 33359401
ROS and hypoxia signaling regulate periodic metabolic arousal during insect dormancy to coordinate glucose, amino acid, and lipid metabolism.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2021 | Pubmed ID: 33372159
Application of Carbon-13 Isotopomer Analysis to Assess Perinatal Myocardial Glucose Metabolism in Sheep.
Metabolites Jan, 2021 | Pubmed ID: 33466367
Deuterated water imaging of the rat brain following metabolism of [ H ]glucose.
Magnetic resonance in medicine 06, 2021 | Pubmed ID: 33576535
Comparison of selective excitation and multi-echo chemical shift encoding for imaging of hyperpolarized [1-C]pyruvate.
Journal of magnetic resonance (San Diego, Calif. : 1997) 04, 2021 | Pubmed ID: 33607386
Intraspecific variation in polar and nonpolar metabolite profiles of a threatened Caribbean coral.
Metabolomics : Official journal of the Metabolomic Society 06, 2021 | Pubmed ID: 34143280
Hyperpolarized Dihydroxyacetone Is a Sensitive Probe of Hepatic Gluconeogenic State.
Metabolites Jul, 2021 | Pubmed ID: 34357335
Measuring NQO1 Bioactivation Using [H]Glucose.
Cancers Aug, 2021 | Pubmed ID: 34439319
INCA 2.0: A tool for integrated, dynamic modeling of NMR- and MS-based isotopomer measurements and rigorous metabolic flux analysis.
Metabolic engineering Jan, 2022 | Pubmed ID: 34965470
Detecting Hepatic Ketogenesis Using Hyperpolarized [2-C] Pyruvate.
Frontiers in physiology , 2022 | Pubmed ID: 35197867
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