N. Joan Abbott

Understanding the Physiology of the Blood-Brain Barrier: In Vitro Models.

Drug resistance in epilepsy: the role of the blood-brain barrier.

Ionic currents in isolated and in situ squid Schwann cells.

Astrocyte-endothelial interactions and blood-brain barrier permeability.

Evaluation of the RBE4 cell line to explore carrier-mediated drug delivery to the CNS via the L-system amino acid transporter at the blood-brain barrier.

Bradykinin increases permeability by calcium and 5-lipoxygenase in the ECV304/C6 cell culture model of the blood-brain barrier.

Interaction between flavonoids and the blood-brain barrier: in vitro studies.

Vascular and parenchymal mechanisms in multiple drug resistance: a lesson from human epilepsy.

Lipids in blood-brain barrier models in vitro I: Thin-layer chromatography and high-performance liquid chromatography for the analysis of lipid classes and long-chain polyunsaturated fatty acids.

Lipids in blood-brain barrier models in vitro II: Influence of glial cells on lipid classes and lipid fatty acids.

Functional characterisation of nucleoside transport in rat brain endothelial cells.

An overview of in vitro techniques for blood-brain barrier studies.

In vitro trans-monolayer permeability calculations: often forgotten assumptions.

Flavonoid permeability across an in situ model of the blood-brain barrier.

Cross reactivity of polyclonal GFAP antiserum: implications for the in-vitro characterisation of brain endothelium.

Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology.

Brain to blood efflux transport of adenosine: blood-brain barrier studies in the rat.

Blood-brain barrier opened by stimulation of the parasympathetic sphenopalatine ganglion: a new method for macromolecule delivery to the brain.

Interaction of nucleoside analogues with nucleoside transporters in rat brain endothelial cells.

Induction of aquaporin 1 but not aquaporin 4 messenger RNA in rat primary brain microvessel endothelial cells in culture.

Dynamics of CNS barriers: evolution, differentiation, and modulation.

Astrocyte-endothelial interactions at the blood-brain barrier.

P-Glycoprotein expression in human retinal pigment epithelium cell lines.

Strategies to advance translational research into brain barriers.

All vertebrates started out with a glial blood-brain barrier 4-500 million years ago.

Structure and function of the blood-brain barrier.

An improved in vitro blood-brain barrier model: rat brain endothelial cells co-cultured with astrocytes.

Establishment of a simplified in vitro porcine blood-brain barrier model with high transendothelial electrical resistance.

Delivery of paclitaxel across cellular barriers using a dendrimer-based nanocarrier.

Overview and introduction: the blood-brain barrier in health and disease.

A detailed method for preparation of a functional and flexible blood-brain barrier model using porcine brain endothelial cells.

Blood-brain barrier structure and function and the challenges for CNS drug delivery.

A multi-system approach assessing the interaction of anticonvulsants with P-gp.

A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1.

Prediction of blood-brain barrier permeation in drug discovery from in vivo, in vitro and in silico models.

In vitro porcine blood-brain barrier model for permeability studies: pCEL-X software pKa(FLUX) method for aqueous boundary layer correction and detailed data analysis.

Primary porcine brain microvessel endothelial cell isolation and culture.

Characterization of a novel brain barrier ex vivo insect-based P-glycoprotein screening model.

The interaction of carbon nanotubes with an in vitro blood-brain barrier model and mouse brain in vivo.

LRP-1-mediated intracellular antibody delivery to the Central Nervous System.

Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood-brain barrier in vitro and in vivo.

In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use.

Bidirectional apical-basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells.

Impact of capillary flow hydrodynamics on carrier-mediated transport of opioid derivatives at the blood-brain barrier, based on pH-dependent Michaelis-Menten and Crone-Renkin analyses.

Uptake and metabolism of sulphated steroids by the blood-brain barrier in the adult male rat.

The blood-brain barrier in psychosis.