Ronald C. Conaway has not added Biography.
If you are Ronald C. Conaway and would like to personalize this page please email our Author Liaison for assistance.
MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression.
The Journal of biological chemistry Jan, 2009 | Pubmed ID: 19049968
Roles of SCF and VHL ubiquitin ligases in regulation of cell growth.
Progress in molecular and subcellular biology , 2002 | Pubmed ID: 11908068
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature Apr, 2002 | Pubmed ID: 11961546
Emerging roles of ubiquitin in transcription regulation.
Science (New York, N.Y.) May, 2002 | Pubmed ID: 12016299
A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase.
The Journal of biological chemistry Aug, 2002 | Pubmed ID: 12048197
Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2002 | Pubmed ID: 12149480
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2002 | Pubmed ID: 12351678
The von Hippel-Lindau tumor suppressor complex and regulation of hypoxia-inducible transcription.
Advances in cancer research , 2002 | Pubmed ID: 12374282
Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex.
The Journal of biological chemistry Mar, 2003 | Pubmed ID: 12538644
Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3.
The Journal of biological chemistry Apr, 2003 | Pubmed ID: 12584197
von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2003 | Pubmed ID: 12604794
The RNA polymerase II elongation complex.
Annual review of biochemistry , 2003 | Pubmed ID: 12676794
TFIIS and GreB: two like-minded transcription elongation factors with sticky fingers.
Cell Aug, 2003 | Pubmed ID: 12914690
Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex.
The Journal of biological chemistry Oct, 2003 | Pubmed ID: 12963728
A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex.
The Journal of biological chemistry Dec, 2003 | Pubmed ID: 14576168
A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2.
The Journal of biological chemistry Feb, 2004 | Pubmed ID: 14638676
Assays for investigating the mechanism of promoter escape by RNA polymerase II.
Methods in enzymology , 2003 | Pubmed ID: 14712687
Preparation and assay of RNA polymerase II elongation factors elongin and ELL.
Methods in enzymology , 2003 | Pubmed ID: 14712707
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.
Molecular cell Jun, 2004 | Pubmed ID: 15175151
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology.
Molecular cell Jun, 2004 | Pubmed ID: 15175163
Identification of Elongin C and Skp1 sequences that determine Cullin selection.
The Journal of biological chemistry Oct, 2004 | Pubmed ID: 15280393
Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.
Molecular and cellular biology Nov, 2004 | Pubmed ID: 15485928
In vivo requirement of the RNA polymerase II elongation factor elongin A for proper gene expression and development.
Molecular and cellular biology Nov, 2004 | Pubmed ID: 15509793
ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex.
The Journal of biological chemistry Feb, 2005 | Pubmed ID: 15590664
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
Genes & development Dec, 2004 | Pubmed ID: 15601820
Regulation of heat shock gene expression by RNA polymerase II elongation factor, Elongin A.
The Journal of biological chemistry Feb, 2005 | Pubmed ID: 15611125
The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes.
The Journal of biological chemistry Apr, 2005 | Pubmed ID: 15647280
The mammalian Mediator complex.
FEBS letters Feb, 2005 | Pubmed ID: 15680972
The mammalian Mediator complex and its role in transcriptional regulation.
Trends in biochemical sciences May, 2005 | Pubmed ID: 15896743
ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2005 | Pubmed ID: 16006523
A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex.
The Journal of biological chemistry Dec, 2005 | Pubmed ID: 16230350
In and out: histone variant exchange in chromatin.
Trends in biochemical sciences Dec, 2005 | Pubmed ID: 16257529
Purification of a human SRCAP complex that remodels chromatin by incorporating the histone variant H2A.Z into nucleosomes.
Biochemistry May, 2006 | Pubmed ID: 16634648
Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1.
Nature cell biology Sep, 2006 | Pubmed ID: 16906146
Purification and assay of the human INO80 and SRCAP chromatin remodeling complexes.
Methods (San Diego, Calif.) Dec, 2006 | Pubmed ID: 17101442
Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2006 | Pubmed ID: 17138671
Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL.
The Journal of biological chemistry Feb, 2007 | Pubmed ID: 17150956
RNA polymerase II: a "nobel" enzyme demystified.
Molecular cell Dec, 2006 | Pubmed ID: 17157247
YY1 functions with INO80 to activate transcription.
Nature structural & molecular biology Sep, 2007 | Pubmed ID: 17721549
Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1.
The Journal of biological chemistry Feb, 2008 | Pubmed ID: 18077452
Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases.
The Journal of biological chemistry Mar, 2008 | Pubmed ID: 18187417
Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2008 | Pubmed ID: 18218781
New clues to actin function in chromatin regulation.
Nature structural & molecular biology May, 2008 | Pubmed ID: 18461045
Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex.
Molecular cell Sep, 2008 | Pubmed ID: 18922472
Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1.
The EMBO journal Dec, 2008 | Pubmed ID: 19037258
The INO80 chromatin remodeling complex in transcription, replication and repair.
Trends in biochemical sciences Feb, 2009 | Pubmed ID: 19062292
Mediator comes out from the shadows.
Structure (London, England : 1993) Apr, 2009 | Pubmed ID: 19368880
Direct inhibition of RNA polymerase II transcription by RECQL5.
The Journal of biological chemistry Aug, 2009 | Pubmed ID: 19570979
Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2009 | Pubmed ID: 19666485
Proteomics reveals a physical and functional link between hepatocyte nuclear factor 4alpha and transcription factor IID.
The Journal of biological chemistry Nov, 2009 | Pubmed ID: 19805548
Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2009 | Pubmed ID: 19920177
Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex.
The Journal of biological chemistry Feb, 2010 | Pubmed ID: 20018852
AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.
Molecular cell Feb, 2010 | Pubmed ID: 20159561
O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1.
Cell Feb, 2011 | Pubmed ID: 21295698
Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling.
The Journal of biological chemistry Apr, 2011 | Pubmed ID: 21303910
Function and regulation of the Mediator complex.
Current opinion in genetics & development Apr, 2011 | Pubmed ID: 21330129
Human mediator subunit MED26 functions as a docking site for transcription elongation factors.
Cell Jul, 2011 | Pubmed ID: 21729782
Origins and activity of the Mediator complex.
Seminars in cell & developmental biology Sep, 2011 | Pubmed ID: 21821140
The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters.
The EMBO journal Sep, 2011 | Pubmed ID: 21822215
Endoplasmic reticulum stress-responsive transcription factor ATF6α directs recruitment of the Mediator of RNA polymerase II transcription and multiple histone acetyltransferase complexes.
The Journal of biological chemistry Jun, 2012 | Pubmed ID: 22577136
The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME.
PloS one , 2012 | Pubmed ID: 22912744
The Mediator complex and transcription elongation.
Biochimica et biophysica acta Jan, 2013 | Pubmed ID: 22983086
Transcriptional elongation factor elongin A regulates retinoic acid-induced gene expression during neuronal differentiation.
Cell reports Nov, 2012 | Pubmed ID: 23122963
Activation of the SNF2 family ATPase ALC1 by poly(ADP-ribose) in a stable ALC1·PARP1·nucleosome intermediate.
The Journal of biological chemistry Dec, 2012 | Pubmed ID: 23132853
Immunoaffinity purification of protein complexes from Mammalian cells.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23436370
A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.
Nature structural & molecular biology May, 2013 | Pubmed ID: 23563140
Transcriptional properties of mammalian elongin A and its role in stress response.
The Journal of biological chemistry Aug, 2013 | Pubmed ID: 23828199
Role for human mediator subunit MED25 in recruitment of mediator to promoters by endoplasmic reticulum stress-responsive transcription factor ATF6α.
The Journal of biological chemistry Sep, 2013 | Pubmed ID: 23864652
Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes.
PLoS genetics Nov, 2013 | Pubmed ID: 24244196
Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2013 | Pubmed ID: 24297934
Subunit architecture and functional modular rearrangements of the transcriptional mediator complex.
Cell Jun, 2014 | Pubmed ID: 24882805
Copyright © 2024 MyJoVE Corporation. 판권 소유