Srividya Bhaskara
Department of Radiation Oncology,
Department of Oncological Sciences,
Huntsman Cancer Institute,
Department of Radiation Oncology, Department of Oncological Sciences, Huntsman Cancer Institute
University of Utah School of Medicine
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Induction of two cytochrome P450 genes, Cyp6a2 and Cyp6a8, of Drosophila melanogaster by caffeine in adult flies and in cell culture.
Gene Aug, 2006 | Pubmed ID: 16713132
Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks.
The EMBO journal Apr, 2008 | Pubmed ID: 18354499
Caffeine induction of Cyp6a2 and Cyp6a8 genes of Drosophila melanogaster is modulated by cAMP and D-JUN protein levels.
Gene May, 2008 | Pubmed ID: 18395996
Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control.
Molecular cell Apr, 2008 | Pubmed ID: 18406327
Deletion of Mtg16, a target of t(16;21), alters hematopoietic progenitor cell proliferation and lineage allocation.
Molecular and cellular biology Oct, 2008 | Pubmed ID: 18710942
The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylation.
The Journal of biological chemistry Aug, 2010 | Pubmed ID: 20538609
Hdac3 is essential for the maintenance of chromatin structure and genome stability.
Cancer cell Nov, 2010 | Pubmed ID: 21075309
Role for histone deacetylase 3 in maintenance of genome stability.
Cell cycle (Georgetown, Tex.) Mar, 2011 | Pubmed ID: 21311228
Analysis of protein dynamics at active, stalled, and collapsed replication forks.
Genes & development Jun, 2011 | Pubmed ID: 21685366
The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells.
Cancer biology & therapy Sep, 2011 | Pubmed ID: 21738006
The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB.
Nucleic acids research Oct, 2012 | Pubmed ID: 23087373
Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma.
PloS one , 2013 | Pubmed ID: 23894374
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.
Cell reports Aug, 2013 | Pubmed ID: 23911289
HDAC3 is essential for DNA replication in hematopoietic progenitor cells.
The Journal of clinical investigation Jul, 2013 | Pubmed ID: 23921131
Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression.
Epigenetics & chromatin , 2013 | Pubmed ID: 23947532
Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells.
Oncotarget Jul, 2014 | Pubmed ID: 25026298
HDAC1,2 inhibition impairs EZH2- and BBAP-mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma.
Oncotarget Mar, 2015 | Pubmed ID: 25605023
Histone deacetylases 1 and 2 regulate DNA replication and DNA repair: potential targets for genome stability-mechanism-based therapeutics for a subset of cancers.
Cell cycle (Georgetown, Tex.) , 2015 | Pubmed ID: 25942572
Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans.
JAMA Nov, 2015 | Pubmed ID: 26447779
Interaction of the Jhd2 Histone H3 Lys-4 Demethylase with Chromatin Is Controlled by Histone H2A Surfaces and Restricted by H2B Ubiquitination.
The Journal of biological chemistry Nov, 2015 | Pubmed ID: 26451043
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