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Department of Emergency Medicine,
Cardiovascular Research Institute,
Department of Physiology
Thomas H. Sanderson has not added Biography.
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Insulin blocks cytochrome c release in the reperfused brain through PI3-K signaling and by promoting Bax/Bcl-XL binding.
Journal of neurochemistry Aug, 2008 | Pubmed ID: 18518905
Insulin activates the PI3K-Akt survival pathway in vulnerable neurons following global brain ischemia.
Neurological research Nov, 2009 | Pubmed ID: 19203442
Hyperoxic reperfusion after global cerebral ischemia promotes inflammation and long-term hippocampal neuronal death.
Journal of neurotrauma Apr, 2010 | Pubmed ID: 20059303
The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis.
Mitochondrion May, 2011 | Pubmed ID: 21296189
Regulation of mitochondrial respiration and apoptosis through cell signaling: cytochrome c oxidase and cytochrome c in ischemia/reperfusion injury and inflammation.
Biochimica et biophysica acta Apr, 2012 | Pubmed ID: 21771582
Phosphorylation of mammalian cytochrome c and cytochrome c oxidase in the regulation of cell destiny: respiration, apoptosis, and human disease.
Advances in experimental medicine and biology , 2012 | Pubmed ID: 22729861
Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Sep, 2012 | Pubmed ID: 22730437
Molecular mechanisms of ischemia-reperfusion injury in brain: pivotal role of the mitochondrial membrane potential in reactive oxygen species generation.
Molecular neurobiology Feb, 2013 | Pubmed ID: 23011809
Mitochondria Dynamics: An Emerging Paradigm In Ischemia-Reperfusion Injury.
Current pharmaceutical design Apr, 2013 | Pubmed ID: 23590157
Wayne State University School of Medicine
Thomas H. Sanderson1,2,3,
Joseph M. Wider2,3
1Department of Emergency Medicine, Wayne State University School of Medicine,
2Cardiovascular Research Institute, Wayne State University School of Medicine,
3Department of Physiology, Wayne State University School of Medicine
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