Y. Eugene Chen

Biochemical characterization and cellular effects of CADASIL mutants of NOTCH3.

A highly efficient method to differentiate smooth muscle cells from human embryonic stem cells.

Rad GTPase deficiency leads to cardiac hypertrophy.

Molecular recognition of nitrated fatty acids by PPAR gamma.

A comparison of murine smooth muscle cells generated from embryonic versus induced pluripotent stem cells.

Gene expression module-based chemical function similarity search.

PPARs and the cardiovascular system.

Beneficial effect of young oocytes for rabbit somatic cell nuclear transfer.

PPARgamma and its ligands: therapeutic implications in cardiovascular disease.

Expression profiling of nuclear receptors in human and mouse embryonic stem cells.

Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation.

Vascular smooth muscle cell-selective peroxisome proliferator-activated receptor-gamma deletion leads to hypotension.

The role of peroxisome proliferator-activated receptor gamma in blood pressure regulation.

Nitro-fatty acid inhibition of neointima formation after endoluminal vessel injury.

Human C-reactive protein does not promote atherosclerosis in transgenic rabbits.

Disruption of inducible 6-phosphofructo-2-kinase ameliorates diet-induced adiposity but exacerbates systemic insulin resistance and adipose tissue inflammatory response.

miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia.

Covalent peroxisome proliferator-activated receptor gamma adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions.

miR-10a contributes to retinoid acid-induced smooth muscle cell differentiation.

Smooth and cardiac muscle-selective knock-out of Kruppel-like factor 4 causes postnatal death and growth retardation.

Peroxisome proliferator-activated receptor delta regulation of miR-15a in ischemia-induced cerebral vascular endothelial injury.

Involvement of inducible 6-phosphofructo-2-kinase in the anti-diabetic effect of peroxisome proliferator-activated receptor gamma activation in mice.

Nitro-oleic acid inhibits angiotensin II-induced hypertension.

Vascular smooth muscle cell peroxisome proliferator-activated receptor-γ deletion promotes abdominal aortic aneurysms.

Porous nanofibrous PLLA scaffolds for vascular tissue engineering.

MicroRNA-1 regulates smooth muscle cell differentiation by repressing Kruppel-like factor 4.

Vascular smooth muscle cell peroxisome proliferator-activated receptor-γ mediates pioglitazone-reduced vascular lesion formation.

Vascular PPARδ protects against stroke-induced brain injury.

Rad GTPase inhibits cardiac fibrosis through connective tissue growth factor.

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis.

Three-dimensional growth of iPS cell-derived smooth muscle cells on nanofibrous scaffolds.

Combined therapeutic strategy to improve vascular endothelial function after implantation of sirolimus-eluting stents.

Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning.

Platelet-derived growth factor induces Rad expression through Egr-1 in vascular smooth muscle cells.

Developmental patterns of PPAR and RXR gene expression during spermatogenesis.

Vascular cell lineage determination and differentiation.

Smooth muscle cell differentiation in vitro: models and underlying molecular mechanisms.

Human apolipoprotein A-I induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through ATP-binding cassette transporter A1.

Monocyte chemotactic protein-induced protein 1 (MCPIP1) suppresses stress granule formation and determines apoptosis under stress.

Inhibition of gluconeogenic genes by calcium-regulated heat-stable protein 1 via repression of peroxisome proliferator-activated receptor α.

Follicular oocytes better support development in rabbit cloning than oviductal oocytes.

Identification and mechanism of 10-carbon fatty acid as modulating ligand of peroxisome proliferator-activated receptors.

Smooth muscle cells for vascular engineering.

MicroRNA and vascular smooth muscle cells.

Endothelial lipase mediates HDL levels in normal and hyperlipidemic rabbits.

Spatial and temporal distribution of Oct-4 and acetylated H4K5 in rabbit embryos.

Yap1 protein regulates vascular smooth muscle cell phenotypic switch by interaction with myocardin.

Mitochondrial dysfunction and adipogenic reduction by prohibitin silencing in 3T3-L1 cells.

A novel strategy for deciphering dynamic conservation of gene expression relationship.

Construction of vascular tissues with macro-porous nano-fibrous scaffolds and smooth muscle cells enriched from differentiated embryonic stem cells.

Vascular endothelial cell-specific microRNA-15a inhibits angiogenesis in hindlimb ischemia.

Recombinant rabbit leukemia inhibitory factor and rabbit embryonic fibroblasts support the derivation and maintenance of rabbit embryonic stem cells.

Disruption of inducible 6-phosphofructo-2-kinase impairs the suppressive effect of PPARγ activation on diet-induced intestine inflammatory response.

Loss of perivascular adipose tissue on peroxisome proliferator-activated receptor-γ deletion in smooth muscle cells impairs intravascular thermoregulation and enhances atherosclerosis.

Dynamic profiles of Oct-4, Cdx-2 and acetylated H4K5 in in-vivo-derived rabbit embryos.

Krüppel-like factor-11, a transcription factor involved in diabetes mellitus, suppresses endothelial cell activation via the nuclear factor-κB signaling pathway.

Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.

Diabetic HDL is dysfunctional in stimulating endothelial cell migration and proliferation due to down regulation of SR-BI expression.

Paradoxical roles of perivascular adipose tissue in atherosclerosis and hypertension.

Human apolipoprotein A-II protects against diet-induced atherosclerosis in transgenic rabbits.

Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β) protein attenuates vascular lesion formation by inhibition of chromatin loading of minichromosome maintenance complex in smooth muscle cells.

Electrophilic nitro-fatty acids inhibit vascular inflammation by disrupting LPS-dependent TLR4 signalling in lipid rafts.

Zc3h12c inhibits vascular inflammation by repressing NF-κB activation and pro-inflammatory gene expression in endothelial cells.

KLF11 mediates PPARγ cerebrovascular protection in ischaemic stroke.

MCPIP1 negatively regulates toll-like receptor 4 signaling and protects mice from LPS-induced septic shock.

Dietary obesity-induced Egr-1 in adipocytes facilitates energy storage via suppression of FOXC2.

Angiogenesis-Regulating microRNAs and Ischemic Stroke.

The Application of SILAC Mouse in Human Body Fluid Proteomics Analysis Reveals Protein Patterns Associated with IgA Nephropathy.

MiR-27 Targets Prohibitin and Impairs Adipocyte Differentiation and Mitochondrial Function in Human Adipose-derived Stem Cells.

SysFinder: A customized platform for search, comparison and assisted design of appropriate animal models based on systematic similarity.

Production of immunodeficient rabbits by multiplex embryo transfer and multiplex gene targeting.

Genomic and Transcriptomic Analysis of Hypercholesterolemic Rabbits: Progress and Perspectives.