Laboratory of Molecular Neurobiology,
Institute of Cellular and Organismic Biology,
Laboratory of Molecular Neurobiology, Institute of Cellular and Organismic Biology
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Tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma stimulate gamma-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway.
The Journal of biological chemistry Nov, 2004 | Pubmed ID: 15347683
Unnatural amino acid-substituted (hydroxyethyl)urea peptidomimetics inhibit gamma-secretase and promote the neuronal differentiation of neuroblastoma cells.
Molecular pharmacology Feb, 2007 | Pubmed ID: 17105873
Sodium selenite inhibits gamma-secretase activity through activation of ERK.
Neuroscience letters Jul, 2008 | Pubmed ID: 18547722
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin.
Molecular biology of the cell Oct, 2008 | Pubmed ID: 18667537
The evolutionarily conserved interaction between LC3 and p62 selectively mediates autophagy-dependent degradation of mutant huntingtin.
Cellular and molecular neurobiology Jul, 2010 | Pubmed ID: 20204693
Caveolin-1 regulates γ-secretase-mediated AβPP processing by modulating spatial distribution of γ-secretase in membrane.
Journal of Alzheimer's disease : JAD , 2010 | Pubmed ID: 20847442
B4GALNT3 expression predicts a favorable prognosis and suppresses cell migration and invasion via β₁ integrin signaling in neuroblastoma.
The American journal of pathology Sep, 2011 | Pubmed ID: 21741930
Nuclear GRP75 binds retinoic acid receptors to promote neuronal differentiation of neuroblastoma.
PloS one , 2011 | Pubmed ID: 22022577
Calreticulin mediates nerve growth factor-induced neuronal differentiation.
Journal of molecular neuroscience : MN Jul, 2012 | Pubmed ID: 22147490
Autophagy: a double-edged sword in Alzheimer's disease.
Journal of biosciences Mar, 2012 | Pubmed ID: 22357213
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy Apr, 2012 | Pubmed ID: 22966490
Retinoic acid-elicited RARα/RXRα signaling attenuates Aβ production by directly inhibiting γ-secretase-mediated cleavage of amyloid precursor protein.
ACS chemical neuroscience Jul, 2013 | Pubmed ID: 23530929
Presenilin-1 regulates the expression of p62 to govern p62-dependent tau degradation.
Molecular neurobiology Feb, 2014 | Pubmed ID: 23794287
The Nogo-C2/Nogo receptor complex regulates the morphogenesis of zebrafish lateral line primordium through modulating the expression of dkk1b, a Wnt signal inhibitor.
PloS one , 2014 | Pubmed ID: 24466042
Aryl hydrocarbon receptor downregulates MYCN expression and promotes cell differentiation of neuroblastoma.
PloS one , 2014 | Pubmed ID: 24586395
Calreticulin activates β1 integrin via fucosylation by fucosyltransferase 1 in J82 human bladder cancer cells.
The Biochemical journal May, 2014 | Pubmed ID: 24593306
Discovery of small molecular (D)-leucinamides as potent, Notch-sparing γ-secretase modulators.
European journal of medicinal chemistry May, 2014 | Pubmed ID: 24732790
JARID1B Expression Plays a Critical Role in Chemoresistance and Stem Cell-Like Phenotype of Neuroblastoma Cells.
PloS one , 2015 | Pubmed ID: 25951238
Multiple signaling factors and drugs alleviate neuronal death induced by expression of human and zebrafish tau proteins in vivo.
Journal of biomedical science Feb, 2016 | Pubmed ID: 26852117
Diagnostic FDG and FDOPA positron emission tomography scans distinguish the genomic type and treatment outcome of neuroblastoma.
Oncotarget Apr, 2016 | Pubmed ID: 26959748
New Hydroxyquinoline-Based Derivatives as Potent Modulators of Amyloid-β Aggregations.
Archiv der Pharmazie May, 2016 | Pubmed ID: 27027880
Epicatechin isolated from Tripterygium wilfordii extract reduces tau-GFP-induced neurotoxicity in zebrafish embryo through the activation of Nrf2.
Biochemical and biophysical research communications 08, 2016 | Pubmed ID: 27301640
A multidisciplinary team care approach improves outcomes in high-risk pediatric neuroblastoma patients.
Oncotarget Jan, 2017 | Pubmed ID: 27966455
ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2017 | Pubmed ID: 28351972
VEGF expression correlates with neuronal differentiation and predicts a favorable prognosis in patients with neuroblastoma.
Scientific reports Sep, 2017 | Pubmed ID: 28894229
Critical Roles of Dual-Specificity Phosphatases in Neuronal Proteostasis and Neurological Diseases.
International journal of molecular sciences Sep, 2017 | Pubmed ID: 28902166
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