Amplification, Purification, and Chemical Modification of Ad Vectors
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Results: Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors
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Conclusion
필기록
This method can help to answer key questions in the field of Gene Therapy, Oncolysis and Genetic Vaccination. It facilitates understanding and modulating of vector hosts interactions of adenovirus gene transfer vectors, the most frequently used ve
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The protocol described here enables researchers to specifically modify adenovirus capsids at selected sites by simple chemistry. Shielded adenovirus vectors particles and retargeted gene transfer vectors can be generated, and vector host interactions can be studied.