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Yongping Wang

Cell and Gene Therapy Laboratory,
Department of Pathology and Laboratory Medicine,
Division of Transfusion Medicine,
Cell and Gene Therapy Laboratory, Department of Pathology and Laboratory Medicine,
Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine

Children’s Hospital of Philadelphia

BIOGRAPHY

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PUBLICATIONS

Manufacturing mesenchymal stromal cells for phase I clinical trials.

Cytotherapy Apr, 2013 | Pubmed ID: 23480951

Introduction of mismatches in a random shRNA-encoding library improves potency for phenotypic selection.

PloS one , 2014 | Pubmed ID: 24498319

CD3/CD19 Depleted Matched and Mismatched Unrelated Donor Hematopoietic Stem Cell Transplant with Targeted T Cell Addback Is Associated with Excellent Outcomes in Pediatric Patients with Nonmalignant Hematologic Disorders.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation Mar, 2019 | Pubmed ID: 30312755

Partially CD3-Depleted Unrelated and Haploidentical Donor Peripheral Stem Cell Transplantation Has Favorable Graft-versus-Host Disease and Survival Rates in Pediatric Hematologic Malignancy.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation Mar, 2020 | Pubmed ID: 31765697

Immune Reconstitution Following TCRαβ/CD19-Depleted Hematopoietic Cell Transplantation for Hematologic Malignancy in Pediatric Patients.

Transplantation and cellular therapy Feb, 2021 | Pubmed ID: 33830028

Unrelated donor α/β T cell- and B cell-depleted HSCT for the treatment of pediatric acute leukemia.

Blood advances Feb, 2022 | Pubmed ID: 34872106

Manufacture and Characterization of Good Manufacturing Practice-Compliant SARS-COV-2 Cytotoxic T Lymphocytes.

The Journal of infectious diseases Mar, 2023 | Pubmed ID: 36583990

A machine-learning model that incorporates CD45 surface expression predicts hematopoietic progenitor cell recovery after freeze-thaw.

Cytotherapy Jun, 2023 | Pubmed ID: 37318396

In vivo hematopoietic stem cell modification by mRNA delivery.

Science (New York, N.Y.) Jul, 2023 | Pubmed ID: 37499029

INSTITUTIONS

Children’s Hospital of Philadelphia

Perelman School of Medicine at the University of Pennsylvania

JOVE ARTICLES

Chimeric Antigen Receptor T Cell Manufacturing on an Automated Cell Processor

Rene Machietto¹,

Nicholas Giacobbe¹,

Jessica Perazzelli²,

Ted J. Hofmann²,

Allison Barz Leahy^2,3,

Stephan A. Grupp^1,2,3,

Yongping Wang^1,3,4,

Stephan Kadauke^1,3,4

¹Cell and Gene Therapy Laboratory, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia,

²Division of Oncology, Department of Pediatrics, Children’s Hospital of Philadelphia,

³, Perelman School of Medicine at the University of Pennsylvania,

⁴Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia

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