Henry M. Colecraft

Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells.

Engineered calmodulins reveal the unexpected eminence of Ca2+ channel inactivation in controlling heart excitation.

Distinctive modulatory effects of five human auxiliary beta2 subunit splice variants on L-type calcium channel gating.

Custom distinctions in the interaction of G-protein beta subunits with N-type (CaV2.2) versus P/Q-type (CaV2.1) calcium channels.

Membrane-associated guanylate kinase-like properties of beta-subunits required for modulation of voltage-dependent Ca2+ channels.

G protein-gated inhibitory module of N-type (ca(v)2.2) ca2+ channels.

A single CaVbeta can reconstitute both trafficking and macroscopic conductance of voltage-dependent calcium channels.

A CaVbeta SH3/guanylate kinase domain interaction regulates multiple properties of voltage-gated Ca2+ channels.

Genetically encoded molecules for inducibly inactivating CaV channels.

Role of CaVbeta subunits, and lack of functional reserve, in protein kinase A modulation of cardiac CaV1.2 channels.

Engineering proteins for custom inhibition of Ca(V) channels.

BIN1 localizes the L-type calcium channel to cardiac T-tubules.

Rem, a member of the RGK GTPases, inhibits recombinant CaV1.2 channels using multiple mechanisms that require distinct conformations of the GTPase.

Molecular mechanisms, and selective pharmacological rescue, of Rem-inhibited CaV1.2 channels in heart.

Mechanism of auxiliary β-subunit-mediated membrane targeting of L-type (Ca(V)1.2) channels.