Kathryn H. Ching

The role of SPECs, small Cdc42-binding proteins, in F-actin accumulation at the immunological synapse.

Biochemical characterization of distinct regions of SPEC molecules and their role in phagocytosis.

Rapid antibody quantification and generation of whole proteome antibody response profiles using LIPS (luciferase immunoprecipitation systems).

Highly quantitative serological detection of anti-cytomegalovirus (CMV) antibodies.

Rapid serological detection of autoantibodies associated with Sjögren's syndrome.

High levels of Anti-GAD65 and Anti-Ro52 autoantibodies in a patient with major depressive disorder showing psychomotor disturbance.

Rapid, simple, quantitative, and highly sensitive antibody detection for lyme disease.

Extraordinary antigenicity of the human Ro52 autoantigen.

Distinct profiles of antibodies to Kaposi sarcoma-associated herpesvirus antigens in patients with Kaposi sarcoma, multicentric Castleman disease, and primary effusion lymphoma.

Antibody-profiling technologies for studying humoral responses to infectious agents.

Proteome-wide anti-hepatitis C virus (HCV) and anti-HIV antibody profiling for predicting and monitoring the response to HCV therapy in HIV-coinfected patients.

Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia.

Synthetic biology for translational research.

Rapid induction of autoantibodies during ARDS and septic shock.

Recombinant expression of the AChR-alpha1 subunit for the detection of conformation-dependent epitopes in Myasthenia Gravis.

LIPS arrays for simultaneous detection of antibodies against partial and whole proteomes of HCV, HIV and EBV.

Emerging tactical strategies for fighting the war on cancer based on the genetic landscape.

Searching for biomarkers: humoral response profiling with luciferase immunoprecipitation systems.

Antibody profiling of Borrelia burgdorferi infection in horses.

Serological studies confirm the novel astrovirus HMOAstV-C as a highly prevalent human infectious agent.